Lee H - Search Results

1

Synthesis and evaluation of an AZD2461 [¹⁸F]PET probe in non-human primates reveals the PARP-1 inhibitor to be non-blood-brain barrier penetrant.

Reilly SW, Puentes LN, Schmitz A, Hsieh CJ, Weng CC, Hou C, Li S, Kuo YM, Padakanti P, Lee H, Riad AA, Makvandi M, Mach RH. Reilly SW, et al. Among authors: lee h. Bioorg Chem. 2019 Mar;83:242-249. doi: 10.1016/j.bioorg.2018.10.015. Epub 2018 Oct 17. Bioorg Chem. 2019. PMID: 30390553 Free PMC article.

2

Synthesis and evaluation of a bromine-76-labeled PPARgamma antagonist 2-bromo-5-nitro-N-phenylbenzamide.

Lee H, Finck BN, Jones LA, Welch MJ, Mach RH. Lee H, et al. Nucl Med Biol. 2006 Oct;33(7):847-54. doi: 10.1016/j.nucmedbio.2006.08.003. Nucl Med Biol. 2006. PMID: 17045164

3

Synthesis and binding affinity of a fluorine-substituted peroxisome proliferator-activated gamma (PPARgamma) ligand as a potential positron emission tomography (PET) imaging agent.

Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Lee BC, et al. Among authors: lee kc, lee h. Bioconjug Chem. 2007 Mar-Apr;18(2):507-13. doi: 10.1021/bc060190o. Epub 2007 Feb 20. Bioconjug Chem. 2007. PMID: 17309226

4

Strategies for the labeling of halogen-substituted peroxisome proliferator-activated receptor gamma ligands: potential positron emission tomography and single photon emission computed tomography imaging agents.

Lee BC, Lee KC, Lee H, Mach RH, Katzenellenbogen JA. Lee BC, et al. Among authors: lee kc, lee h. Bioconjug Chem. 2007 Mar-Apr;18(2):514-23. doi: 10.1021/bc060191g. Epub 2007 Feb 23. Bioconjug Chem. 2007. PMID: 17315977

5

Design and synthesis of 2-amino-4-methylpyridine analogues as inhibitors for inducible nitric oxide synthase and in vivo evaluation of [18F]6-(2-fluoropropyl)-4-methyl-pyridin-2-amine as a potential PET tracer for inducible nitric oxide synthase.

Zhou D, Lee H, Rothfuss JM, Chen DL, Ponde DE, Welch MJ, Mach RH. Zhou D, et al. Among authors: lee h. J Med Chem. 2009 Apr 23;52(8):2443-53. doi: 10.1021/jm801556h. J Med Chem. 2009. PMID: 19323559 Free PMC article.

6

Click synthesis and biologic evaluation of (R)- and (S)-2-amino-3-[1-(2-[18F]fluoroethyl)-1H-[1,2,3]triazol-4-yl]propanoic acid for brain tumor imaging with positron emission tomography.

McConathy J, Zhou D, Shockley SE, Jones LA, Griffin EA, Lee H, Adams SJ, Mach RH. McConathy J, et al. Among authors: lee h. Mol Imaging. 2010 Dec;9(6):329-42. Mol Imaging. 2010. PMID: 21084029

7

Synthesis and evaluation of 18F-labeled PPARγ antagonists.

Lee H, Chen DL, Rothfuss JM, Welch MJ, Gropler RJ, Mach RH. Lee H, et al. Nucl Med Biol. 2012 Jan;39(1):77-87. doi: 10.1016/j.nucmedbio.2011.07.002. Epub 2011 Sep 9. Nucl Med Biol. 2012. PMID: 21907585 Free PMC article.

8

[(18)F]FluorThanatrace uptake as a marker of PARP1 expression and activity in breast cancer.

Edmonds CE, Makvandi M, Lieberman BP, Xu K, Zeng C, Li S, Hou C, Lee H, Greenberg RA, Mankoff DA, Mach RH. Edmonds CE, et al. Among authors: lee h. Am J Nucl Med Mol Imaging. 2016 Jan 28;6(1):94-101. eCollection 2016. Am J Nucl Med Mol Imaging. 2016. PMID: 27069769 Free PMC article.

9

PARP-1 Expression Quantified by [¹⁸F]FluorThanatrace: A Biomarker of Response to PARP Inhibition Adjuvant to Radiation Therapy.

Sander Effron S, Makvandi M, Lin L, Xu K, Li S, Lee H, Hou C, Pryma DA, Koch C, Mach RH. Sander Effron S, et al. Among authors: lee h. Cancer Biother Radiopharm. 2017 Feb;32(1):9-15. doi: 10.1089/cbr.2016.2133. Epub 2017 Jan 24. Cancer Biother Radiopharm. 2017. PMID: 28118040 Free PMC article.

10

[¹⁸F](2S,4R)4-Fluoroglutamine PET Detects Glutamine Pool Size Changes in Triple-Negative Breast Cancer in Response to Glutaminase Inhibition.

Zhou R, Pantel AR, Li S, Lieberman BP, Ploessl K, Choi H, Blankemeyer E, Lee H, Kung HF, Mach RH, Mankoff DA. Zhou R, et al. Among authors: lee h. Cancer Res. 2017 Mar 15;77(6):1476-1484. doi: 10.1158/0008-5472.CAN-16-1945. Epub 2017 Feb 15. Cancer Res. 2017. PMID: 28202527 Free PMC article.

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