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Enhanced potency of bivalent small molecule gp41 inhibitors.
Sofiyev V, Kaur H, Snyder BA, Hogan PA, Ptak RG, Hwang P, Gochin M. Sofiyev V, et al. Among authors: ptak rg. Bioorg Med Chem. 2017 Jan 1;25(1):408-420. doi: 10.1016/j.bmc.2016.11.010. Epub 2016 Nov 19. Bioorg Med Chem. 2017. PMID: 27908751 Free PMC article.
Potent strategy to inhibit HIV-1 by binding both gp120 and gp41.
Kagiampakis I, Gharibi A, Mankowski MK, Snyder BA, Ptak RG, Alatas K, LiWang PJ. Kagiampakis I, et al. Among authors: ptak rg. Antimicrob Agents Chemother. 2011 Jan;55(1):264-75. doi: 10.1128/AAC.00376-10. Epub 2010 Oct 18. Antimicrob Agents Chemother. 2011. PMID: 20956603 Free PMC article.
An analog of camptothecin inactive against Topoisomerase I is broadly neutralizing of HIV-1 through inhibition of Vif-dependent APOBEC3G degradation.
Bennett RP, Stewart RA, Hogan PA, Ptak RG, Mankowski MK, Hartman TL, Buckheit RW Jr, Snyder BA, Salter JD, Morales GA, Smith HC. Bennett RP, et al. Among authors: ptak rg. Antiviral Res. 2016 Dec;136:51-59. doi: 10.1016/j.antiviral.2016.11.001. Epub 2016 Nov 5. Antiviral Res. 2016. PMID: 27825797 Free PMC article.
Development of a comprehensive human immunodeficiency virus type 1 screening algorithm for discovery and preclinical testing of topical microbicides.
Lackman-Smith C, Osterling C, Luckenbaugh K, Mankowski M, Snyder B, Lewis G, Paull J, Profy A, Ptak RG, Buckheit RW Jr, Watson KM, Cummins JE Jr, Sanders-Beer BE. Lackman-Smith C, et al. Among authors: ptak rg. Antimicrob Agents Chemother. 2008 May;52(5):1768-81. doi: 10.1128/AAC.01328-07. Epub 2008 Mar 3. Antimicrob Agents Chemother. 2008. PMID: 18316528 Free PMC article.
93 results