Finel M - Search Results

1

A Novel Pathogenic UGT1A1 Variant in a Sudanese Child with Type 1 Crigler-Najjar Syndrome.

Elfar W, Järvinen E, Ji W, Mosorin J, Sega AG, Iuga AC, Lobritto SJ, Konstantino M, Chan A, Finel M, Lakhani SA. Elfar W, et al. Among authors: finel m. Drug Metab Dispos. 2019 Jan;47(1):45-48. doi: 10.1124/dmd.118.084368. Epub 2018 Nov 1. Drug Metab Dispos. 2019. PMID: 30385458

2

Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity.

Troberg J, Järvinen E, Muniz M, Sneitz N, Mosorin J, Hagström M, Finel M. Troberg J, et al. Among authors: finel m. Drug Metab Dispos. 2015 Jan;43(1):107-18. doi: 10.1124/dmd.114.059303. Epub 2014 Oct 9. Drug Metab Dispos. 2015. PMID: 25301937

3

Regiospecificity and stereospecificity of human UDP-glucuronosyltransferases in the glucuronidation of estriol, 16-epiestriol, 17-epiestriol, and 13-epiestradiol.

Sneitz N, Vahermo M, Mosorin J, Laakkonen L, Poirier D, Finel M. Sneitz N, et al. Among authors: finel m. Drug Metab Dispos. 2013 Mar;41(3):582-91. doi: 10.1124/dmd.112.049072. Epub 2013 Jan 3. Drug Metab Dispos. 2013. PMID: 23288867

4

Case report by Toce and co-authors: Have all the reasons for poor morphine glucuronidation been addressed?

Finel M, Järvinen E. Finel M, et al. Br J Clin Pharmacol. 2019 Apr;85(4):859-860. doi: 10.1111/bcp.13868. Epub 2019 Feb 8. Br J Clin Pharmacol. 2019. PMID: 30737810 Free PMC article. No abstract available.

5

Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7.

Kallionpää RA, Järvinen E, Finel M. Kallionpää RA, et al. Among authors: finel m. J Steroid Biochem Mol Biol. 2015 Nov;154:104-11. doi: 10.1016/j.jsbmb.2015.07.013. Epub 2015 Jul 26. J Steroid Biochem Mol Biol. 2015. PMID: 26220143

6

Human efflux transport of testosterone, epitestosterone and other androgen glucuronides.

Järvinen E, Kidron H, Finel M. Järvinen E, et al. Among authors: finel m. J Steroid Biochem Mol Biol. 2020 Mar;197:105518. doi: 10.1016/j.jsbmb.2019.105518. Epub 2019 Nov 6. J Steroid Biochem Mol Biol. 2020. PMID: 31704245

7

Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.

Järvinen E, Troberg J, Kidron H, Finel M. Järvinen E, et al. Among authors: finel m. Mol Pharm. 2017 Oct 2;14(10):3299-3311. doi: 10.1021/acs.molpharmaceut.7b00366. Epub 2017 Sep 13. Mol Pharm. 2017. PMID: 28850245

8

Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.

Järvinen E, Deng F, Kidron H, Finel M. Järvinen E, et al. Among authors: finel m. J Steroid Biochem Mol Biol. 2018 Apr;178:99-107. doi: 10.1016/j.jsbmb.2017.11.007. Epub 2017 Nov 22. J Steroid Biochem Mol Biol. 2018. PMID: 29175180

9

UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?

Troberg J, Järvinen E, Ge GB, Yang L, Finel M. Troberg J, et al. Among authors: finel m. Mol Pharm. 2017 Sep 5;14(9):2875-2883. doi: 10.1021/acs.molpharmaceut.6b00852. Epub 2016 Dec 14. Mol Pharm. 2017. PMID: 27966992

10

Crigler-Najjar syndrome in The Netherlands: identification of four novel UGT1A1 alleles, genotype-phenotype correlation, and functional analysis of 10 missense mutants.

Sneitz N, Bakker CT, de Knegt RJ, Halley DJ, Finel M, Bosma PJ. Sneitz N, et al. Among authors: finel m. Hum Mutat. 2010 Jan;31(1):52-9. doi: 10.1002/humu.21133. Hum Mutat. 2010. PMID: 19830808

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