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Under expression of the Sonic Hedgehog receptor, Patched1 (PTCH1), is associated with an increased risk of local recurrence in squamous cell carcinoma of the vulva arising on a background of Lichen Sclerosus.
Yap J, Fox R, Narsia N, Pinheiro-Maia S, Pounds R, Woodman C, Luesley D, Ganesan R, Kehoe S, Dawson C. Yap J, et al. Among authors: narsia n. PLoS One. 2018 Oct 31;13(10):e0206553. doi: 10.1371/journal.pone.0206553. eCollection 2018. PLoS One. 2018. PMID: 30379908 Free PMC article.