Eccles SA - Search Results

1

Metabolic biomarkers of response to the AKT inhibitor MK-2206 in pre-clinical models of human colorectal and prostate carcinoma.

Al-Saffar NMS, Troy H, Wong Te Fong AC, Paravati R, Jackson LE, Gowan S, Boult JKR, Robinson SP, Eccles SA, Yap TA, Leach MO, Chung YL. Al-Saffar NMS, et al. Among authors: eccles sa. Br J Cancer. 2018 Oct;119(9):1118-1128. doi: 10.1038/s41416-018-0242-3. Epub 2018 Oct 31. Br J Cancer. 2018. PMID: 30377337 Free PMC article.

2

The phosphocholine and glycerophosphocholine content of an oestrogen-sensitive rat mammary tumour correlates strongly with growth rate.

Smith TA, Eccles S, Ormerod MG, Tombs AJ, Titley JC, Leach MO. Smith TA, et al. Br J Cancer. 1991 Nov;64(5):821-6. doi: 10.1038/bjc.1991.407. Br J Cancer. 1991. PMID: 1931601 Free PMC article.

3

The effect of oestrogen ablation on the phospholipid metabolite content of primary and transplanted rat mammary tumours.

Smith TA, Baluch S, Titley JC, Ormerod MG, Eccles S, Tombs AJ, Leach MO, Griffiths JR, McCready VR. Smith TA, et al. NMR Biomed. 1993 May-Jun;6(3):209-14. doi: 10.1002/nbm.1940060307. NMR Biomed. 1993. PMID: 8347455

4

Phosphocholine and choline content of rat sarcoma cells grown in the presence and absence of serum.

Smith TA, Eccles S, Box G, Titley JC, Leach MO, McCready VR. Smith TA, et al. Anticancer Res. 1996 May-Jun;16(3B):1389-92. Anticancer Res. 1996. PMID: 8694506

5

Identification of magnetic resonance detectable metabolic changes associated with inhibition of phosphoinositide 3-kinase signaling in human breast cancer cells.

Beloueche-Babari M, Jackson LE, Al-Saffar NM, Eccles SA, Raynaud FI, Workman P, Leach MO, Ronen SM. Beloueche-Babari M, et al. Among authors: eccles sa. Mol Cancer Ther. 2006 Jan;5(1):187-96. doi: 10.1158/1535-7163.MCT-03-0220. Mol Cancer Ther. 2006. PMID: 16432178

6

Benzoquinone ansamycin heat shock protein 90 inhibitors modulate multiple functions required for tumor angiogenesis.

Sanderson S, Valenti M, Gowan S, Patterson L, Ahmad Z, Workman P, Eccles SA. Sanderson S, et al. Among authors: eccles sa. Mol Cancer Ther. 2006 Mar;5(3):522-32. doi: 10.1158/1535-7163.MCT-05-0439. Mol Cancer Ther. 2006. PMID: 16546966

7

Pharmacologic characterization of a potent inhibitor of class I phosphatidylinositide 3-kinases.

Raynaud FI, Eccles S, Clarke PA, Hayes A, Nutley B, Alix S, Henley A, Di-Stefano F, Ahmad Z, Guillard S, Bjerke LM, Kelland L, Valenti M, Patterson L, Gowan S, de Haven Brandon A, Hayakawa M, Kaizawa H, Koizumi T, Ohishi T, Patel S, Saghir N, Parker P, Waterfield M, Workman P. Raynaud FI, et al. Cancer Res. 2007 Jun 15;67(12):5840-50. doi: 10.1158/0008-5472.CAN-06-4615. Cancer Res. 2007. PMID: 17575152 Free article.

8

Application of meso scale technology for the measurement of phosphoproteins in human tumor xenografts.

Gowan SM, Hardcastle A, Hallsworth AE, Valenti MR, Hunter LJ, de Haven Brandon AK, Garrett MD, Raynaud F, Workman P, Aherne W, Eccles SA. Gowan SM, et al. Among authors: eccles sa. Assay Drug Dev Technol. 2007 Jun;5(3):391-401. doi: 10.1089/adt.2006.044. Assay Drug Dev Technol. 2007. PMID: 17638539

9

The Bcl-2/Bcl-XL family inhibitor ABT-737 sensitizes ovarian cancer cells to carboplatin.

Witham J, Valenti MR, De-Haven-Brandon AK, Vidot S, Eccles SA, Kaye SB, Richardson A. Witham J, et al. Among authors: eccles sa. Clin Cancer Res. 2007 Dec 1;13(23):7191-8. doi: 10.1158/1078-0432.CCR-07-0362. Clin Cancer Res. 2007. PMID: 18056200

10

NVP-AUY922: a novel heat shock protein 90 inhibitor active against xenograft tumor growth, angiogenesis, and metastasis.

Eccles SA, Massey A, Raynaud FI, Sharp SY, Box G, Valenti M, Patterson L, de Haven Brandon A, Gowan S, Boxall F, Aherne W, Rowlands M, Hayes A, Martins V, Urban F, Boxall K, Prodromou C, Pearl L, James K, Matthews TP, Cheung KM, Kalusa A, Jones K, McDonald E, Barril X, Brough PA, Cansfield JE, Dymock B, Drysdale MJ, Finch H, Howes R, Hubbard RE, Surgenor A, Webb P, Wood M, Wright L, Workman P. Eccles SA, et al. Cancer Res. 2008 Apr 15;68(8):2850-60. doi: 10.1158/0008-5472.CAN-07-5256. Cancer Res. 2008. PMID: 18413753

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