Mayans O - Search Results

1

Evolutionary Morphing of Tryptophan Synthase: Functional Mechanisms for the Enzymatic Channeling of Indole.

Fleming JR, Schupfner M, Busch F, Baslé A, Ehrmann A, Sterner R, Mayans O. Fleming JR, et al. Among authors: mayans o. J Mol Biol. 2018 Dec 7;430(24):5066-5079. doi: 10.1016/j.jmb.2018.10.013. Epub 2018 Oct 25. J Mol Biol. 2018. PMID: 30367843

2

Structural and mutational analysis of substrate complexation by anthranilate phosphoribosyltransferase from Sulfolobus solfataricus.

Marino M, Deuss M, Svergun DI, Konarev PV, Sterner R, Mayans O. Marino M, et al. Among authors: mayans o. J Biol Chem. 2006 Jul 28;281(30):21410-21421. doi: 10.1074/jbc.M601403200. Epub 2006 May 19. J Biol Chem. 2006. PMID: 16714288 Free article.

3

A rationally designed monomeric variant of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus is as active as the dimeric wild-type enzyme but less thermostable.

Schwab T, Skegro D, Mayans O, Sterner R. Schwab T, et al. Among authors: mayans o. J Mol Biol. 2008 Feb 15;376(2):506-16. doi: 10.1016/j.jmb.2007.11.078. Epub 2007 Dec 4. J Mol Biol. 2008. PMID: 18164726

4

Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release.

Schlee S, Deuss M, Bruning M, Ivens A, Schwab T, Hellmann N, Mayans O, Sterner R. Schlee S, et al. Among authors: mayans o. Biochemistry. 2009 Jun 16;48(23):5199-209. doi: 10.1021/bi802335s. Biochemistry. 2009. PMID: 19385665

5

Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line.

Bogomolovas J, Gasch A, Simkovic F, Rigden DJ, Labeit S, Mayans O. Bogomolovas J, et al. Among authors: mayans o. Open Biol. 2014 May;4(5):140041. doi: 10.1098/rsob.140041. Open Biol. 2014. PMID: 24850911 Free PMC article.

6

TrpB2 enzymes are O-phospho-l-serine dependent tryptophan synthases.

Busch F, Rajendran C, Mayans O, Löffler P, Merkl R, Sterner R. Busch F, et al. Among authors: mayans o. Biochemistry. 2014 Sep 30;53(38):6078-83. doi: 10.1021/bi500977y. Epub 2014 Sep 17. Biochemistry. 2014. PMID: 25184516

7

Titin and obscurin: giants holding hands and discovery of a new Ig domain subset.

Benian GM, Mayans O. Benian GM, et al. Among authors: mayans o. J Mol Biol. 2015 Feb 27;427(4):707-714. doi: 10.1016/j.jmb.2014.12.017. Epub 2014 Dec 31. J Mol Biol. 2015. PMID: 25555989 Free PMC article. No abstract available.

8

CARP interacts with titin at a unique helical N2A sequence and at the domain Ig81 to form a structured complex.

Zhou T, Fleming JR, Franke B, Bogomolovas J, Barsukov I, Rigden DJ, Labeit S, Mayans O. Zhou T, et al. Among authors: mayans o. FEBS Lett. 2016 Sep;590(18):3098-110. doi: 10.1002/1873-3468.12362. Epub 2016 Sep 2. FEBS Lett. 2016. PMID: 27531639 Free article.

9

Exploration of pathomechanisms triggered by a single-nucleotide polymorphism in titin's I-band: the cardiomyopathy-linked mutation T2580I.

Bogomolovas J, Fleming JR, Anderson BR, Williams R, Lange S, Simon B, Khan MM, Rudolf R, Franke B, Bullard B, Rigden DJ, Granzier H, Labeit S, Mayans O. Bogomolovas J, et al. Among authors: mayans o. Open Biol. 2016 Sep;6(9):160114. doi: 10.1098/rsob.160114. Open Biol. 2016. PMID: 27683155 Free PMC article.

10

Autophosphorylation Is a Mechanism of Inhibition in Twitchin Kinase.

Williams RM, Franke B, Wilkinson M, Fleming JR, Rigden DJ, Benian GM, Eyers PA, Mayans O. Williams RM, et al. Among authors: mayans o. J Mol Biol. 2018 Mar 16;430(6):793-805. doi: 10.1016/j.jmb.2018.01.020. Epub 2018 Feb 3. J Mol Biol. 2018. PMID: 29408381

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