Yang J - Search Results

1

Identifying the novel inhibitors of lysine-specific demethylase 1 (LSD1) combining pharmacophore-based and structure-based virtual screening.

Sun XD, Zheng YC, Ma CY, Yang J, Gao QB, Yan Y, Wang ZZ, Li W, Zhao W, Liu HM, Ding L. Sun XD, et al. Among authors: yang j. J Biomol Struct Dyn. 2019 Oct;37(16):4200-4214. doi: 10.1080/07391102.2018.1538903. Epub 2018 Dec 5. J Biomol Struct Dyn. 2019. PMID: 30366512

2

Design and synthesis of tranylcypromine derivatives as novel LSD1/HDACs dual inhibitors for cancer treatment.

Duan YC, Ma YC, Qin WP, Ding LN, Zheng YC, Zhu YL, Zhai XY, Yang J, Ma CY, Guan YY. Duan YC, et al. Among authors: yang j. Eur J Med Chem. 2017 Nov 10;140:392-402. doi: 10.1016/j.ejmech.2017.09.038. Epub 2017 Sep 21. Eur J Med Chem. 2017. PMID: 28987602

3

Probing the binding mechanism of substituted pyridine derivatives as effective and selective lysine-specific demethylase 1 inhibitors using 3D-QSAR, molecular docking and molecular dynamics simulations.

Wang ZZ, Yang J, Sun XD, Ma CY, Gao QB, Ding L, Liu HM. Wang ZZ, et al. Among authors: yang j. J Biomol Struct Dyn. 2019 Aug;37(13):3482-3495. doi: 10.1080/07391102.2018.1518158. Epub 2018 Dec 5. J Biomol Struct Dyn. 2019. PMID: 30175693

4

Discovery and structure-activity relationships of ent-Kaurene diterpenoids as potent and selective 11β-HSD1 inhibitors: potential impact in diabetes.

Deng X, Shen Y, Yang J, He J, Zhao Y, Peng LY, Leng Y, Zhao QS. Deng X, et al. Among authors: yang j. Eur J Med Chem. 2013 Jul;65:403-14. doi: 10.1016/j.ejmech.2013.05.010. Epub 2013 May 18. Eur J Med Chem. 2013. PMID: 23747808

5

Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.

Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y. Lan JS, et al. Among authors: yang j. Eur J Med Chem. 2017 Jun 16;133:184-196. doi: 10.1016/j.ejmech.2017.02.045. Epub 2017 Mar 23. Eur J Med Chem. 2017. PMID: 28388521

6

S3I-201 derivative incorporating naphthoquinone unit as effective STAT3 inhibitors: Design, synthesis and anti-gastric cancer evaluation.

Li H, Cai M, Cao F, Yu D, Yang J, Yu W, Chu C, Guan X, Qin JJ, Dong J. Li H, et al. Among authors: yang j. Bioorg Med Chem. 2022 Oct 1;71:116941. doi: 10.1016/j.bmc.2022.116941. Epub 2022 Jul 19. Bioorg Med Chem. 2022. PMID: 35944386

7

Synthesis and quantitative structure-activity relationships study for phenylpropenamide derivatives as inhibitors of hepatitis B virus replication.

Yang J, Ma M, Wang XD, Jiang XJ, Zhang YY, Yang WQ, Li ZC, Wang XH, Yang B, Ma ML. Yang J, et al. Among authors: yang b, yang wq. Eur J Med Chem. 2015 Jun 24;99:82-91. doi: 10.1016/j.ejmech.2015.05.032. Epub 2015 May 28. Eur J Med Chem. 2015. PMID: 26057705

8

Design, synthesis and evaluation of resveratrol-indazole hybrids as novel monoamine oxidases inhibitors with amyloid-β aggregation inhibition.

Lan JS, Liu Y, Hou JW, Yang J, Zhang XY, Zhao Y, Xie SS, Ding Y, Zhang T. Lan JS, et al. Among authors: yang j. Bioorg Chem. 2018 Feb;76:130-139. doi: 10.1016/j.bioorg.2017.11.009. Epub 2017 Nov 15. Bioorg Chem. 2018. PMID: 29172101

9

Discovery of benzochalcone derivative as a potential antigastric cancer agent targeting signal transducer and activator of transcription 3 (STAT3).

Dong J, Yang J, Yu W, Li H, Cai M, Xu JL, Xu HD, Shi YF, Guan X, Cheng XD, Qin JJ. Dong J, et al. Among authors: yang j. J Enzyme Inhib Med Chem. 2022 Dec;37(1):2004-2016. doi: 10.1080/14756366.2022.2100366. J Enzyme Inhib Med Chem. 2022. PMID: 35844184 Free PMC article.

10

Aspeterreurone A, a Cytotoxic Dihydrobenzofuran-Phenyl Acrylate Hybrid from the Deep-Sea-Derived Fungus Aspergillus terreus CC-S06-18.

Wang W, Yang J, Liao YY, Cheng G, Chen J, Mo S, Yuan L, Cheng XD, Qin JJ, Shao Z. Wang W, et al. Among authors: yang j. J Nat Prod. 2020 Jun 26;83(6):1998-2003. doi: 10.1021/acs.jnatprod.0c00189. Epub 2020 Jun 3. J Nat Prod. 2020. PMID: 32489099

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