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Structure-Based Optimization of N-Substituted Oseltamivir Derivatives as Potent Anti-Influenza A Virus Agents with Significantly Improved Potency against Oseltamivir-Resistant N1-H274Y Variant.
Zhang J, Murugan NA, Tian Y, Bertagnin C, Fang Z, Kang D, Kong X, Jia H, Sun Z, Jia R, Gao P, Poongavanam V, Loregian A, Xu W, Ma X, Ding X, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: jia r, jia h. J Med Chem. 2018 Nov 21;61(22):9976-9999. doi: 10.1021/acs.jmedchem.8b01065. Epub 2018 Nov 6. J Med Chem. 2018. PMID: 30365885
Optimization of N-Substituted Oseltamivir Derivatives as Potent Inhibitors of Group-1 and -2 Influenza A Neuraminidases, Including a Drug-Resistant Variant.
Zhang J, Poongavanam V, Kang D, Bertagnin C, Lu H, Kong X, Ju H, Lu X, Gao P, Tian Y, Jia H, Desta S, Ding X, Sun L, Fang Z, Huang B, Liang X, Jia R, Ma X, Xu W, Murugan NA, Loregian A, Huang B, Zhan P, Liu X. Zhang J, et al. Among authors: jia r, jia h. J Med Chem. 2018 Jul 26;61(14):6379-6397. doi: 10.1021/acs.jmedchem.8b00929. Epub 2018 Jul 16. J Med Chem. 2018. PMID: 29965752
6,610 results