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Page 1
Phenotypic and molecular dissection of metaplastic breast cancer and the prognostic implications.
McCart Reed AE, Kalaw E, Nones K, Bettington M, Lim M, Bennett J, Johnstone K, Kutasovic JR, Saunus JM, Kazakoff S, Xu Q, Wood S, Holmes O, Leonard C, Reid LE, Black D, Niland C, Ferguson K, Gresshoff I, Raghavendra A, Harvey K, Cooper C, Liu C, Kalinowski L, Reid AS, Davidson M, Pearson JV, Pathmanathan N, Tse G, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox SB, O'Toole SA, Simpson PT, Waddell N, Lakhani SR. McCart Reed AE, et al. Among authors: gresshoff i. J Pathol. 2019 Feb;247(2):214-227. doi: 10.1002/path.5184. Epub 2018 Dec 20. J Pathol. 2019. PMID: 30350370
Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1.
Kalaw E, Lim M, Kutasovic JR, Sokolova A, Taege L, Johnstone K, Bennett J, Saunus JM, Niland C, Ferguson K, Gresshoff I, Bettington M, Pathmanathan N, Tse GM, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox S, O'Toole SA, Simpson PT, Lakhani SR, McCart Reed AE. Kalaw E, et al. Among authors: gresshoff i. Br J Cancer. 2020 Nov;123(11):1665-1672. doi: 10.1038/s41416-020-01065-3. Epub 2020 Sep 17. Br J Cancer. 2020. PMID: 32939056 Free PMC article.
Epigenome erosion and SOX10 drive neural crest phenotypic mimicry in triple-negative breast cancer.
Saunus JM, De Luca XM, Northwood K, Raghavendra A, Hasson A, McCart Reed AE, Lim M, Lal S, Vargas AC, Kutasovic JR, Dalley AJ, Miranda M, Kalaw E, Kalita-de Croft P, Gresshoff I, Al-Ejeh F, Gee JMW, Ormandy C, Khanna KK, Beesley J, Chenevix-Trench G, Green AR, Rakha EA, Ellis IO, Nicolau DV Jr, Simpson PT, Lakhani SR. Saunus JM, et al. Among authors: gresshoff i. NPJ Breast Cancer. 2022 May 2;8(1):57. doi: 10.1038/s41523-022-00425-x. NPJ Breast Cancer. 2022. PMID: 35501337 Free PMC article.
COMMD3 loss drives invasive breast cancer growth by modulating copper homeostasis.
Hancock JL, Kalimutho M, Straube J, Lim M, Gresshoff I, Saunus JM, Lee JS, Lakhani SR, Simpson KJ, Bush AI, Anderson RL, Khanna KK. Hancock JL, et al. Among authors: gresshoff i. J Exp Clin Cancer Res. 2023 Apr 18;42(1):90. doi: 10.1186/s13046-023-02663-8. J Exp Clin Cancer Res. 2023. PMID: 37072858 Free PMC article.
Resistance to CDK2 inhibitors is associated with selection of polyploid cells in CCNE1-amplified ovarian cancer.
Etemadmoghadam D, Au-Yeung G, Wall M, Mitchell C, Kansara M, Loehrer E, Batzios C, George J, Ftouni S, Weir BA, Carter S, Gresshoff I, Mileshkin L, Rischin D, Hahn WC, Waring PM, Getz G, Cullinane C, Campbell LJ, Bowtell DD. Etemadmoghadam D, et al. Among authors: gresshoff i. Clin Cancer Res. 2013 Nov 1;19(21):5960-71. doi: 10.1158/1078-0432.CCR-13-1337. Epub 2013 Sep 4. Clin Cancer Res. 2013. PMID: 24004674
Mutations in TRPV4 cause an inherited arthropathy of hands and feet.
Lamandé SR, Yuan Y, Gresshoff IL, Rowley L, Belluoccio D, Kaluarachchi K, Little CB, Botzenhart E, Zerres K, Amor DJ, Cole WG, Savarirayan R, McIntyre P, Bateman JF. Lamandé SR, et al. Among authors: gresshoff il. Nat Genet. 2011 Oct 2;43(11):1142-6. doi: 10.1038/ng.945. Nat Genet. 2011. PMID: 21964574
Cartilage-specific ablation of XBP1 signaling in mouse results in a chondrodysplasia characterized by reduced chondrocyte proliferation and delayed cartilage maturation and mineralization.
Cameron TL, Gresshoff IL, Bell KM, Piróg KA, Sampurno L, Hartley CL, Sanford EM, Wilson R, Ermann J, Boot-Handford RP, Glimcher LH, Briggs MD, Bateman JF. Cameron TL, et al. Among authors: gresshoff il. Osteoarthritis Cartilage. 2015 Apr;23(4):661-70. doi: 10.1016/j.joca.2015.01.001. Epub 2015 Jan 17. Osteoarthritis Cartilage. 2015. PMID: 25600960 Free article.