Chu W - Search Results

1

Copper-Mediated Nucleophilic Radiobromination of Aryl Boron Precursors: Convenient Preparation of a Radiobrominated PARP-1 Inhibitor.

Zhou D, Chu W, Voller T, Katzenellenbogen JA. Zhou D, et al. Among authors: chu w. Tetrahedron Lett. 2018 May 16;59(20):1963-1967. doi: 10.1016/j.tetlet.2018.04.024. Epub 2018 Apr 11. Tetrahedron Lett. 2018. PMID: 30349147 Free PMC article.

2

Synthesis, radiolabeling, and in vivo evaluation of an 18F-labeled isatin analog for imaging caspase-3 activation in apoptosis.

Zhou D, Chu W, Rothfuss J, Zeng C, Xu J, Jones L, Welch MJ, Mach RH. Zhou D, et al. Among authors: chu w. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5041-6. doi: 10.1016/j.bmcl.2006.07.045. Epub 2006 Aug 7. Bioorg Med Chem Lett. 2006. PMID: 16891117

3

Isatin sulfonamide analogs containing a Michael addition acceptor: a new class of caspase 3/7 inhibitors.

Chu W, Rothfuss J, d'Avignon A, Zeng C, Zhou D, Hotchkiss RS, Mach RH. Chu W, et al. J Med Chem. 2007 Jul 26;50(15):3751-5. doi: 10.1021/jm070506t. Epub 2007 Jun 23. J Med Chem. 2007. PMID: 17585855

4

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Chu W, Xu J, Zhou D, Zhang F, Jones LA, Wheeler KT, Mach RH. Chu W, et al. Bioorg Med Chem. 2009 Feb 1;17(3):1222-31. doi: 10.1016/j.bmc.2008.12.025. Epub 2008 Dec 24. Bioorg Med Chem. 2009. PMID: 19119012 Free PMC article.

5

[18F]- and [11C]-labeled N-benzyl-isatin sulfonamide analogues as PET tracers for apoptosis: synthesis, radiolabeling mechanism, and in vivo imaging study of apoptosis in Fas-treated mice using [11C]WC-98.

Zhou D, Chu W, Chen DL, Wang Q, Reichert DE, Rothfuss J, D'Avignon A, Welch MJ, Mach RH. Zhou D, et al. Among authors: chu w. Org Biomol Chem. 2009 Apr 7;7(7):1337-48. doi: 10.1039/b819024k. Epub 2009 Feb 16. Org Biomol Chem. 2009. PMID: 19300818 Free PMC article.

6

Synthesis and in vitro evaluation of sulfonamide isatin Michael acceptors as small molecule inhibitors of caspase-6.

Chu W, Rothfuss J, Chu Y, Zhou D, Mach RH. Chu W, et al. Among authors: chu y. J Med Chem. 2009 Apr 23;52(8):2188-91. doi: 10.1021/jm900135r. J Med Chem. 2009. PMID: 19326941

7

Comparison of radiolabeled isatin analogs for imaging apoptosis with positron emission tomography.

Chen DL, Zhou D, Chu W, Herrbrich PE, Jones LA, Rothfuss JM, Engle JT, Geraci M, Welch MJ, Mach RH. Chen DL, et al. Among authors: chu w. Nucl Med Biol. 2009 Aug;36(6):651-8. doi: 10.1016/j.nucmedbio.2009.03.008. Nucl Med Biol. 2009. PMID: 19647171 Free PMC article.

8

Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay.

Chu W, Rothfuss J, Zhou D, Mach RH. Chu W, et al. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2192-7. doi: 10.1016/j.bmcl.2011.03.015. Bioorg Med Chem Lett. 2011. PMID: 21441025 Free PMC article.

9

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site.

Xu J, Zeng C, Chu W, Pan F, Rothfuss JM, Zhang F, Tu Z, Zhou D, Zeng D, Vangveravong S, Johnston F, Spitzer D, Chang KC, Hotchkiss RS, Hawkins WG, Wheeler KT, Mach RH. Xu J, et al. Among authors: chu w. Nat Commun. 2011 Jul 5;2:380. doi: 10.1038/ncomms1386. Nat Commun. 2011. PMID: 21730960 Free PMC article.

10

Radiolabeled isatin binding to caspase-3 activation induced by anti-Fas antibody.

Chen DL, Zhou D, Chu W, Herrbrich P, Engle JT, Griffin E, Jones LA, Rothfuss JM, Geraci M, Hotchkiss RS, Mach RH. Chen DL, et al. Among authors: chu w. Nucl Med Biol. 2012 Jan;39(1):137-44. doi: 10.1016/j.nucmedbio.2011.08.001. Epub 2011 Oct 26. Nucl Med Biol. 2012. PMID: 22033021 Free PMC article.

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