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A road map for prioritizing warheads for cysteine targeting covalent inhibitors.
Ábrányi-Balogh P, Petri L, Imre T, Szijj P, Scarpino A, Hrast M, Mitrović A, Fonovič UP, Németh K, Barreteau H, Roper DI, Horváti K, Ferenczy GG, Kos J, Ilaš J, Gobec S, Keserű GM. Ábrányi-Balogh P, et al. Among authors: szijj p. Eur J Med Chem. 2018 Dec 5;160:94-107. doi: 10.1016/j.ejmech.2018.10.010. Epub 2018 Oct 6. Eur J Med Chem. 2018. PMID: 30321804
Cysteine specific bioconjugation with benzyl isothiocyanates.
Petri L, Szijj PA, Kelemen Á, Imre T, Gömöry Á, Lee MTW, Hegedűs K, Ábrányi-Balogh P, Chudasama V, Keserű GM. Petri L, et al. Among authors: szijj pa. RSC Adv. 2020 Apr 16;10(25):14928-14936. doi: 10.1039/d0ra02934c. eCollection 2020 Apr 8. RSC Adv. 2020. PMID: 35497170 Free PMC article.
Tyrosine bioconjugation - an emergent alternative.
Szijj PA, Kostadinova KA, Spears RJ, Chudasama V. Szijj PA, et al. Org Biomol Chem. 2020 Nov 28;18(44):9018-9028. doi: 10.1039/d0ob01912g. Epub 2020 Nov 3. Org Biomol Chem. 2020. PMID: 33141139 Free PMC article. Review.
Site-Selective Antibody Conjugation with Dibromopyrazines.
Szepesi Kovács D, Pásztor B, Ábrányi-Balogh P, Petri L, Imre T, Simon J, Tátrai E, Várady G, Tóvári J, Szijj PA, Keserű GM. Szepesi Kovács D, et al. Among authors: szijj pa. Bioconjug Chem. 2024 Sep 18;35(9):1373-1379. doi: 10.1021/acs.bioconjchem.4c00296. Epub 2024 Aug 16. Bioconjug Chem. 2024. PMID: 39151068 Free PMC article.
16 results