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Page 1
Cycling CD4+ T cells in HIV-infected immune nonresponders have mitochondrial dysfunction.
Younes SA, Talla A, Pereira Ribeiro S, Saidakova EV, Korolevskaya LB, Shmagel KV, Shive CL, Freeman ML, Panigrahi S, Zweig S, Balderas R, Margolis L, Douek DC, Anthony DD, Pandiyan P, Cameron M, Sieg SF, Calabrese LH, Rodriguez B, Lederman MM. Younes SA, et al. Among authors: douek dc. J Clin Invest. 2018 Nov 1;128(11):5083-5094. doi: 10.1172/JCI120245. Epub 2018 Oct 15. J Clin Invest. 2018. PMID: 30320604 Free PMC article. Clinical Trial.
HIV preferentially infects HIV-specific CD4+ T cells.
Douek DC, Brenchley JM, Betts MR, Ambrozak DR, Hill BJ, Okamoto Y, Casazza JP, Kuruppu J, Kunstman K, Wolinsky S, Grossman Z, Dybul M, Oxenius A, Price DA, Connors M, Koup RA. Douek DC, et al. Nature. 2002 May 2;417(6884):95-8. doi: 10.1038/417095a. Nature. 2002. PMID: 11986671
Sometimes help may not be enough.
Lederman MM, Douek DC. Lederman MM, et al. Among authors: douek dc. AIDS. 2003 May 23;17(8):1249-51. doi: 10.1097/00002030-200305230-00018. AIDS. 2003. PMID: 12819528 No abstract available.
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. Brenchley JM, et al. Among authors: douek dc. Nat Med. 2006 Dec;12(12):1365-71. doi: 10.1038/nm1511. Epub 2006 Nov 19. Nat Med. 2006. PMID: 17115046
HIV infection and the gastrointestinal immune system.
Brenchley JM, Douek DC. Brenchley JM, et al. Among authors: douek dc. Mucosal Immunol. 2008 Jan;1(1):23-30. doi: 10.1038/mi.2007.1. Mucosal Immunol. 2008. PMID: 19079157 Free PMC article. Review.
Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection.
Jiang W, Lederman MM, Hunt P, Sieg SF, Haley K, Rodriguez B, Landay A, Martin J, Sinclair E, Asher AI, Deeks SG, Douek DC, Brenchley JM. Jiang W, et al. Among authors: douek dc. J Infect Dis. 2009 Apr 15;199(8):1177-85. doi: 10.1086/597476. J Infect Dis. 2009. PMID: 19265479 Free PMC article. Clinical Trial.
Evaluation of the pathogenesis of decreasing CD4(+) T cell counts in human immunodeficiency virus type 1-infected patients receiving successfully suppressive antiretroviral therapy.
Nies-Kraske E, Schacker TW, Condoluci D, Orenstein J, Brenchley J, Fox C, Daucher M, Dewar R, Urban E, Hill B, Guenaga J, Hoover S, Maldarelli F, Hallahan CW, Horn J, Kottilil S, Chun TW, Folino M, Palmer S, Wiegand A, O'Shea MA, Metcalf JA, Douek DC, Coffin J, Haase A, Fauci AS, Dybul M. Nies-Kraske E, et al. Among authors: douek dc. J Infect Dis. 2009 Jun 1;199(11):1648-56. doi: 10.1086/598980. J Infect Dis. 2009. PMID: 19432547 Free PMC article.
460 results