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Blocking integrin α4β7-mediated CD4 T cell recruitment to the intestine and liver protects mice from western diet-induced non-alcoholic steatohepatitis.
Rai RP, Liu Y, Iyer SS, Liu S, Gupta B, Desai C, Kumar P, Smith T, Singhi AD, Nusrat A, Parkos CA, Monga SP, Czaja MJ, Anania FA, Raeman R. Rai RP, et al. Among authors: raeman r. J Hepatol. 2020 Nov;73(5):1013-1022. doi: 10.1016/j.jhep.2020.05.047. Epub 2020 Jun 12. J Hepatol. 2020. PMID: 32540177 Free PMC article.
Autotaxin determines colitis severity in mice and is secreted by B cells in the colon.
Lin S, Haque A, Raeman R, Guo L, He P, Denning TL, El-Rayes B, Moolenaar WH, Yun CC. Lin S, et al. Among authors: raeman r. FASEB J. 2019 Mar;33(3):3623-3635. doi: 10.1096/fj.201801415RR. Epub 2018 Nov 27. FASEB J. 2019. PMID: 30481488 Free PMC article.
Our study suggests that pharmacological inhibition of ATX could be a therapeutic strategy in colitis.-Lin, S., Haque, A., Raeman, R., Guo, L., He, P., Denning, T. L., El-Rayes, B., Moolenaar, W. H., Yun, C. C. ...
Our study suggests that pharmacological inhibition of ATX could be a therapeutic strategy in colitis.-Lin, S., Haque, A., Raeman, …
[No title available]
[No authors listed] [No authors listed] PMID: 35557273
23 results