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Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.
Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME. Haure-Mirande JV, et al. Among authors: zhang b. Mol Psychiatry. 2019 Mar;24(3):431-446. doi: 10.1038/s41380-018-0255-6. Epub 2018 Oct 3. Mol Psychiatry. 2019. PMID: 30283032 Free PMC article.
Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in a tauopathy mouse model reduces C1q and normalizes clinical phenotype while increasing spread and state of phosphorylation of tau.
Audrain M, Haure-Mirande JV, Wang M, Kim SH, Fanutza T, Chakrabarty P, Fraser P, St George-Hyslop PH, Golde TE, Blitzer RD, Schadt EE, Zhang B, Ehrlich ME, Gandy S. Audrain M, et al. Among authors: zhang b. Mol Psychiatry. 2019 Sep;24(9):1383-1397. doi: 10.1038/s41380-018-0258-3. Epub 2018 Oct 3. Mol Psychiatry. 2019. PMID: 30283031 Free PMC article.
Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.
Haure-Mirande JV, Wang M, Audrain M, Fanutza T, Kim SH, Heja S, Readhead B, Dudley JT, Blitzer RD, Schadt EE, Zhang B, Gandy S, Ehrlich ME. Haure-Mirande JV, et al. Among authors: zhang b. Mol Psychiatry. 2019 Mar;24(3):472. doi: 10.1038/s41380-018-0301-4. Mol Psychiatry. 2019. PMID: 30464330 Free PMC article.
Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.
Beckmann ND, Lin WJ, Wang M, Cohain AT, Charney AW, Wang P, Ma W, Wang YC, Jiang C, Audrain M, Comella PH, Fakira AK, Hariharan SP, Belbin GM, Girdhar K, Levey AI, Seyfried NT, Dammer EB, Duong D, Lah JJ, Haure-Mirande JV, Shackleton B, Fanutza T, Blitzer R, Kenny E, Zhu J, Haroutunian V, Katsel P, Gandy S, Tu Z, Ehrlich ME, Zhang B, Salton SR, Schadt EE. Beckmann ND, et al. Among authors: zhang b. Nat Commun. 2020 Aug 7;11(1):3942. doi: 10.1038/s41467-020-17405-z. Nat Commun. 2020. PMID: 32770063 Free PMC article.
CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.
Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, Zimmer M, Paull D, Zhang B, Schadt EE, Ehrlich ME, Tanzi RE, Arancio O, Noggle S, Gandy S. Ortiz-Virumbrales M, et al. Among authors: zhang b. Acta Neuropathol Commun. 2017 Oct 27;5(1):77. doi: 10.1186/s40478-017-0475-z. Acta Neuropathol Commun. 2017. PMID: 29078805 Free PMC article.
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.
McKenzie AT, Moyon S, Wang M, Katsyv I, Song WM, Zhou X, Dammer EB, Duong DM, Aaker J, Zhao Y, Beckmann N, Wang P, Zhu J, Lah JJ, Seyfried NT, Levey AI, Katsel P, Haroutunian V, Schadt EE, Popko B, Casaccia P, Zhang B. McKenzie AT, et al. Among authors: zhang b. Mol Neurodegener. 2017 Nov 6;12(1):82. doi: 10.1186/s13024-017-0219-3. Mol Neurodegener. 2017. PMID: 29110684 Free PMC article.
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