Lu C - Search Results

1

Effects of 3D culturing conditions on the transcriptomic profile of stem-cell-derived neurons.

Tekin H, Simmons S, Cummings B, Gao L, Adiconis X, Hession CC, Ghoshal A, Dionne D, Choudhury SR, Yesilyurt V, Sanjana NE, Shi X, Lu C, Heidenreich M, Pan JQ, Levin JZ, Zhang F. Tekin H, et al. Among authors: lu c. Nat Biomed Eng. 2018 Jul;2(7):540-554. doi: 10.1038/s41551-018-0219-9. Epub 2018 Apr 9. Nat Biomed Eng. 2018. PMID: 30271673 Free PMC article.

2

Micro-electrode array recordings reveal reductions in both excitation and inhibition in cultured cortical neuron networks lacking Shank3.

Lu C, Chen Q, Zhou T, Bozic D, Fu Z, Pan JQ, Feng G. Lu C, et al. Mol Psychiatry. 2016 Feb;21(2):159-68. doi: 10.1038/mp.2015.173. Epub 2015 Nov 24. Mol Psychiatry. 2016. PMID: 26598066

3

Mice with Shank3 Mutations Associated with ASD and Schizophrenia Display Both Shared and Distinct Defects.

Zhou Y, Kaiser T, Monteiro P, Zhang X, Van der Goes MS, Wang D, Barak B, Zeng M, Li C, Lu C, Wells M, Amaya A, Nguyen S, Lewis M, Sanjana N, Zhou Y, Zhang M, Zhang F, Fu Z, Feng G. Zhou Y, et al. Among authors: lu c. Neuron. 2016 Jan 6;89(1):147-62. doi: 10.1016/j.neuron.2015.11.023. Epub 2015 Dec 10. Neuron. 2016. PMID: 26687841 Free PMC article.

4

Overexpression of NEUROG2 and NEUROG1 in human embryonic stem cells produces a network of excitatory and inhibitory neurons.

Lu C, Shi X, Allen A, Baez-Nieto D, Nikish A, Sanjana NE, Pan JQ. Lu C, et al. FASEB J. 2019 Apr;33(4):5287-5299. doi: 10.1096/fj.201801110RR. Epub 2019 Jan 30. FASEB J. 2019. PMID: 30698461 Free PMC article.

Our findings not only extend our understanding of the NEUROG2/1-induced human neuronal network but also substantiate NEUROG2/1 iNs as an in vitro system for modeling neuronal and functional deficits on a human genetic background.-Lu, C., Shi, X., Allen, A., Baez-Nie …

Our findings not only extend our understanding of the NEUROG2/1-induced human neuronal network but also substantiate NEUROG2/1 iNs as an in …

5

Generation of a knock-in MAP2-tdTomato reporter human embryonic stem cell line with inducible expression of NEUROG2/1 (NYGCe001-A).

Lu C, Sanjana NE. Lu C, et al. Stem Cell Res. 2019 Dec;41:101643. doi: 10.1016/j.scr.2019.101643. Epub 2019 Nov 1. Stem Cell Res. 2019. PMID: 31707212 Free PMC article.

6

Pluripotent stem cell-derived models of neurological diseases reveal early transcriptional heterogeneity.

Sorek M, Oweis W, Nissim-Rafinia M, Maman M, Simon S, Hession CC, Adiconis X, Simmons SK, Sanjana NE, Shi X, Lu C, Pan JQ, Xu X, Pouladi MA, Ellerby LM, Zhang F, Levin JZ, Meshorer E. Sorek M, et al. Among authors: lu c. Genome Biol. 2021 Mar 4;22(1):73. doi: 10.1186/s13059-021-02301-6. Genome Biol. 2021. PMID: 33663567 Free PMC article.

7

The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.

Garipler G, Lu C, Morrissey A, Lopez-Zepeda LS, Pei Y, Vidal SE, Zen Petisco Fiore AP, Aydin B, Stadtfeld M, Ohler U, Mahony S, Sanjana NE, Mazzoni EO. Garipler G, et al. Among authors: lu c. Cell Rep. 2022 Mar 15;38(11):110524. doi: 10.1016/j.celrep.2022.110524. Cell Rep. 2022. PMID: 35294876 Free PMC article.

8

A genome-scale screen for synthetic drivers of T cell proliferation.

Legut M, Gajic Z, Guarino M, Daniloski Z, Rahman JA, Xue X, Lu C, Lu L, Mimitou EP, Hao S, Davoli T, Diefenbach C, Smibert P, Sanjana NE. Legut M, et al. Among authors: lu l, lu c. Nature. 2022 Mar;603(7902):728-735. doi: 10.1038/s41586-022-04494-7. Epub 2022 Mar 16. Nature. 2022. PMID: 35296855 Free PMC article.

9

Heterozygous deletion of the autism-associated gene CHD8 impairs synaptic function through widespread changes in gene expression and chromatin compaction.

Shi X, Lu C, Corman A, Nikish A, Zhou Y, Platt RJ, Iossifov I, Zhang F, Pan JQ, Sanjana NE. Shi X, et al. Among authors: lu c. Am J Hum Genet. 2023 Oct 5;110(10):1750-1768. doi: 10.1016/j.ajhg.2023.09.004. Am J Hum Genet. 2023. PMID: 37802044 Free PMC article.

10

Essential transcription factors for induced neuron differentiation.

Lu C, Garipler G, Dai C, Roush T, Salome-Correa J, Martin A, Liscovitch-Brauer N, Mazzoni EO, Sanjana NE. Lu C, et al. Nat Commun. 2023 Dec 15;14(1):8362. doi: 10.1038/s41467-023-43602-7. Nat Commun. 2023. PMID: 38102126 Free PMC article.

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