Chang L - Search Results

1

Design, synthesis, and biological activity of substituted 2-amino-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid derivatives as inhibitors of the inflammatory kinases TBK1 and IKKε for the treatment of obesity.

Beyett TS, Gan X, Reilly SM, Gomez AV, Chang L, Tesmer JJG, Saltiel AR, Showalter HD. Beyett TS, et al. Among authors: chang l. Bioorg Med Chem. 2018 Nov 1;26(20):5443-5461. doi: 10.1016/j.bmc.2018.09.020. Epub 2018 Sep 20. Bioorg Med Chem. 2018. PMID: 30270002 Free PMC article.

2

The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes.

Chang L, Adams RD, Saltiel AR. Chang L, et al. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12835-40. doi: 10.1073/pnas.202495599. Epub 2002 Sep 19. Proc Natl Acad Sci U S A. 2002. PMID: 12242347 Free PMC article.

3

The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin.

Inoue M, Chang L, Hwang J, Chiang SH, Saltiel AR. Inoue M, et al. Among authors: chang l. Nature. 2003 Apr 10;422(6932):629-33. doi: 10.1038/nature01533. Nature. 2003. PMID: 12687004 Free article.

4

Insulin signaling and the regulation of glucose transport.

Chang L, Chiang SH, Saltiel AR. Chang L, et al. Mol Med. 2004 Jul-Dec;10(7-12):65-71. doi: 10.2119/2005-00029.Saltiel. Mol Med. 2004. PMID: 16307172 Free PMC article. Review.

5

TC10 and insulin-stimulated glucose transport.

Chiang SH, Chang L, Saltiel AR. Chiang SH, et al. Among authors: chang l. Methods Enzymol. 2006;406:701-14. doi: 10.1016/S0076-6879(06)06055-1. Methods Enzymol. 2006. PMID: 16472699

6

Compartmentalization of the exocyst complex in lipid rafts controls Glut4 vesicle tethering.

Inoue M, Chiang SH, Chang L, Chen XW, Saltiel AR. Inoue M, et al. Among authors: chang l. Mol Biol Cell. 2006 May;17(5):2303-11. doi: 10.1091/mbc.e06-01-0030. Epub 2006 Mar 8. Mol Biol Cell. 2006. PMID: 16525015 Free PMC article.

7

TC10alpha is required for insulin-stimulated glucose uptake in adipocytes.

Chang L, Chiang SH, Saltiel AR. Chang L, et al. Endocrinology. 2007 Jan;148(1):27-33. doi: 10.1210/en.2006-1167. Epub 2006 Sep 28. Endocrinology. 2007. PMID: 17008399

8

Gapex-5, a Rab31 guanine nucleotide exchange factor that regulates Glut4 trafficking in adipocytes.

Lodhi IJ, Chiang SH, Chang L, Vollenweider D, Watson RT, Inoue M, Pessin JE, Saltiel AR. Lodhi IJ, et al. Among authors: chang l. Cell Metab. 2007 Jan;5(1):59-72. doi: 10.1016/j.cmet.2006.12.006. Cell Metab. 2007. PMID: 17189207 Free PMC article.

9

TC10 is regulated by caveolin in 3T3-L1 adipocytes.

Bridges D, Chang L, Lodhi IJ, Clark NA, Saltiel AR. Bridges D, et al. Among authors: chang l. PLoS One. 2012;7(8):e42451. doi: 10.1371/journal.pone.0042451. Epub 2012 Aug 10. PLoS One. 2012. PMID: 22900022 Free PMC article.

10

An inhibitor of the protein kinases TBK1 and IKK-ɛ improves obesity-related metabolic dysfunctions in mice.

Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, Li P, Olefsky JM, Saltiel AR. Reilly SM, et al. Among authors: chang l. Nat Med. 2013 Mar;19(3):313-21. doi: 10.1038/nm.3082. Epub 2013 Feb 10. Nat Med. 2013. PMID: 23396211 Free PMC article.

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