Bolanos B - Search Results

1

Reviving B-Factors: Activating ALK Mutations Increase Protein Dynamics of the Unphosphorylated Kinase.

Johnson TW, Bolanos B, Brooun A, Gallego RA, Gehlhaar D, Jalaie M, McTigue M, Timofeevski S. Johnson TW, et al. Among authors: bolanos b. ACS Med Chem Lett. 2018 Aug 24;9(9):872-877. doi: 10.1021/acsmedchemlett.8b00348. eCollection 2018 Sep 13. ACS Med Chem Lett. 2018. PMID: 30258533 Free PMC article.

2

The Axl kinase domain in complex with a macrocyclic inhibitor offers first structural insights into an active TAM receptor kinase.

Gajiwala KS, Grodsky N, Bolaños B, Feng J, Ferre R, Timofeevski S, Xu M, Murray BW, Johnson TW, Stewart A. Gajiwala KS, et al. Among authors: bolanos b. J Biol Chem. 2017 Sep 22;292(38):15705-15716. doi: 10.1074/jbc.M116.771485. Epub 2017 Jul 19. J Biol Chem. 2017. PMID: 28724631 Free PMC article.

3

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Falk MD, Liu W, Bolaños B, Unsal-Kacmaz K, Klippel A, Grant S, Brooun A, Timofeevski S. Falk MD, et al. Among authors: bolanos b. Biosci Rep. 2014 Apr 1;34(2):e00097. doi: 10.1042/BSR20140010. Print 2014 Apr 1. Biosci Rep. 2014. PMID: 27919031 Free PMC article.

4

Structural and biophysical characterization of XIAP BIR3 G306E mutant: insights in protein dynamics and application for fragment-based drug design.

Moore CD, Wu H, Bolaños B, Bergqvist S, Brooun A, Pauly T, Nowlin D. Moore CD, et al. Among authors: bolanos b. Chem Biol Drug Des. 2009 Sep;74(3):212-23. doi: 10.1111/j.1747-0285.2009.00862.x. Epub 2009 Jul 29. Chem Biol Drug Des. 2009. PMID: 19660030

5

Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.

Brooun A, Gajiwala KS, Deng YL, Liu W, Bolaños B, Bingham P, He YA, Diehl W, Grable N, Kung PP, Sutton S, Maegley KA, Yu X, Stewart AE. Brooun A, et al. Among authors: bolanos b. Nat Commun. 2016 Apr 28;7:11384. doi: 10.1038/ncomms11384. Nat Commun. 2016. PMID: 27122193 Free PMC article.

6

Conserved RNA-binding specificity of polycomb repressive complex 2 is achieved by dispersed amino acid patches in EZH2.

Long Y, Bolanos B, Gong L, Liu W, Goodrich KJ, Yang X, Chen S, Gooding AR, Maegley KA, Gajiwala KS, Brooun A, Cech TR, Liu X. Long Y, et al. Among authors: bolanos b. Elife. 2017 Nov 29;6:e31558. doi: 10.7554/eLife.31558. Elife. 2017. PMID: 29185984 Free PMC article.

7

Development of a long acting human growth hormone analog suitable for once a week dosing.

Palanki MS, Bhat A, Bolanos B, Brunel F, Del Rosario J, Dettling D, Horn M, Lappe R, Preston R, Sievers A, Stankovic N, Woodnut G, Chen G. Palanki MS, et al. Among authors: bolanos b. Bioorg Med Chem Lett. 2013 Jan 15;23(2):402-6. doi: 10.1016/j.bmcl.2012.11.104. Epub 2012 Dec 5. Bioorg Med Chem Lett. 2013. PMID: 23253442

8

Dissecting the molecular determinants of clinical PARP1 inhibitor selectivity for tankyrase1.

Ryan K, Bolaňos B, Smith M, Palde PB, Cuenca PD, VanArsdale TL, Niessen S, Zhang L, Behenna D, Ornelas MA, Tran KT, Kaiser S, Lum L, Stewart A, Gajiwala KS. Ryan K, et al. Among authors: bolanos b. J Biol Chem. 2021 Jan-Jun;296:100251. doi: 10.1074/jbc.RA120.016573. Epub 2021 Jan 9. J Biol Chem. 2021. PMID: 33361107 Free PMC article.

9

[No title available]

[No authors listed] [No authors listed] PMID: 33428942

10

Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants.

Greasley SE, Noell S, Plotnikova O, Ferre R, Liu W, Bolanos B, Fennell K, Nicki J, Craig T, Zhu Y, Stewart AE, Steppan CM. Greasley SE, et al. Among authors: bolanos b. J Biol Chem. 2022 Jun;298(6):101972. doi: 10.1016/j.jbc.2022.101972. Epub 2022 Apr 22. J Biol Chem. 2022. PMID: 35461811 Free PMC article.

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