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Page 1
COPD-Type lung inflammation promotes K-ras mutant lung cancer through epithelial HIF-1α mediated tumor angiogenesis and proliferation.
De la Garza MM, Cumpian AM, Daliri S, Castro-Pando S, Umer M, Gong L, Khosravi N, Caetano MS, Ramos-Castañeda M, Flores AG, Beltran EC, Tran HT, Tuvim MJ, Ostrin EJ, Dickey BF, Evans CM, Moghaddam SJ. De la Garza MM, et al. Among authors: cumpian am. Oncotarget. 2018 Aug 31;9(68):32972-32983. doi: 10.18632/oncotarget.26030. eCollection 2018 Aug 31. Oncotarget. 2018. PMID: 30250643 Free PMC article.
Tumor necrosis factor links chronic obstructive pulmonary disease and K-ras mutant lung cancer through induction of an immunosuppressive pro-tumor microenvironment.
Gong L, da Silva Caetano M, Cumpian AM, Daliri S, Garza Flores A, Chang SH, Ochoa CE, Evans CM, Yu Z, Moghaddam SJ. Gong L, et al. Among authors: cumpian am. Oncoimmunology. 2016 Sep 2;5(10):e1229724. doi: 10.1080/2162402X.2016.1229724. eCollection 2016. Oncoimmunology. 2016. PMID: 27853654 Free PMC article.
Reduced IL-6 levels and tumor-associated phospho-STAT3 are associated with reduced tumor development in a mouse model of lung cancer chemoprevention with myo-inositol.
Unver N, Delgado O, Zeleke K, Cumpian A, Tang X, Caetano MS, Wang H, Katayama H, Yu H, Szabo E, Wistuba II, Moghaddam SJ, Hanash SM, Ostrin EJ. Unver N, et al. Int J Cancer. 2018 Apr 1;142(7):1405-1417. doi: 10.1002/ijc.31152. Epub 2017 Dec 23. Int J Cancer. 2018. PMID: 29134640 Free PMC article.
T helper 17 cells play a critical pathogenic role in lung cancer.
Chang SH, Mirabolfathinejad SG, Katta H, Cumpian AM, Gong L, Caetano MS, Moghaddam SJ, Dong C. Chang SH, et al. Among authors: cumpian am. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5664-9. doi: 10.1073/pnas.1319051111. Epub 2014 Mar 31. Proc Natl Acad Sci U S A. 2014. PMID: 24706787 Free PMC article.
IL6 Blockade Reprograms the Lung Tumor Microenvironment to Limit the Development and Progression of K-ras-Mutant Lung Cancer.
Caetano MS, Zhang H, Cumpian AM, Gong L, Unver N, Ostrin EJ, Daliri S, Chang SH, Ochoa CE, Hanash S, Behrens C, Wistuba II, Sternberg C, Kadara H, Ferreira CG, Watowich SS, Moghaddam SJ. Caetano MS, et al. Among authors: cumpian am. Cancer Res. 2016 Jun 1;76(11):3189-99. doi: 10.1158/0008-5472.CAN-15-2840. Epub 2016 Apr 1. Cancer Res. 2016. PMID: 27197187 Free PMC article.
IL22 Promotes Kras-Mutant Lung Cancer by Induction of a Protumor Immune Response and Protection of Stemness Properties.
Khosravi N, Caetano MS, Cumpian AM, Unver N, De la Garza Ramos C, Noble O, Daliri S, Hernandez BJ, Gutierrez BA, Evans SE, Hanash S, Alekseev AM, Yang Y, Chang SH, Nurieva R, Kadara H, Chen J, Ostrin EJ, Moghaddam SJ. Khosravi N, et al. Among authors: cumpian am. Cancer Immunol Res. 2018 Jul;6(7):788-797. doi: 10.1158/2326-6066.CIR-17-0655. Epub 2018 May 15. Cancer Immunol Res. 2018. PMID: 29764837 Free PMC article.
Requirement for MUC5AC in KRAS-dependent lung carcinogenesis.
Bauer AK, Umer M, Richardson VL, Cumpian AM, Harder AQ, Khosravi N, Azzegagh Z, Hara NM, Ehre C, Mohebnasab M, Caetano MS, Merrick DT, van Bokhoven A, Wistuba II, Kadara H, Dickey BF, Velmurugan K, Mann PR, Lu X, Barón AE, Evans CM, Moghaddam SJ. Bauer AK, et al. Among authors: cumpian am. JCI Insight. 2018 Aug 9;3(15):e120941. doi: 10.1172/jci.insight.120941. eCollection 2018 Aug 9. JCI Insight. 2018. PMID: 30089720 Free PMC article.
Sex specific function of epithelial STAT3 signaling in pathogenesis of K-ras mutant lung cancer.
Caetano MS, Hassane M, Van HT, Bugarin E, Cumpian AM, McDowell CL, Cavazos CG, Zhang H, Deng S, Diao L, Wang J, Evans SE, Behrens C, Wistuba II, Fuqua SAW, Lin H, Stabile LP, Watowich SS, Kadara H, Moghaddam SJ. Caetano MS, et al. Among authors: cumpian am. Nat Commun. 2018 Nov 2;9(1):4589. doi: 10.1038/s41467-018-07042-y. Nat Commun. 2018. PMID: 30389925 Free PMC article.