Huls G - Search Results

1

Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones.

de Boer B, Prick J, Pruis MG, Keane P, Imperato MR, Jaques J, Brouwers-Vos AZ, Hogeling SM, Woolthuis CM, Nijk MT, Diepstra A, Wandinger S, Versele M, Attar RM, Cockerill PN, Huls G, Vellenga E, Mulder AB, Bonifer C, Schuringa JJ. de Boer B, et al. Among authors: huls g. Cancer Cell. 2018 Oct 8;34(4):674-689.e8. doi: 10.1016/j.ccell.2018.08.014. Epub 2018 Sep 20. Cancer Cell. 2018. PMID: 30245083 Free article.

2

AML at older age: age-related gene expression profiles reveal a paradoxical down-regulation of p16INK4A mRNA with prognostic significance.

de Jonge HJ, de Bont ES, Valk PJ, Schuringa JJ, Kies M, Woolthuis CM, Delwel R, Veeger NJ, Vellenga E, Löwenberg B, Huls G. de Jonge HJ, et al. Among authors: huls g. Blood. 2009 Oct 1;114(14):2869-77. doi: 10.1182/blood-2009-03-212688. Epub 2009 Aug 10. Blood. 2009. PMID: 19667402 Free article.

3

Paradoxical down-regulation of p16 mRNA with advancing age in acute myeloid leukemia.

de Jonge HJ, Woolthuis CM, de Bont ES, Huls G. de Jonge HJ, et al. Among authors: huls g. Aging (Albany NY). 2009 Oct 23;1(11):949-53. doi: 10.18632/aging.100096. Aging (Albany NY). 2009. PMID: 20157576 Free PMC article.

4

Efficacy of single-agent lenalidomide in patients with JAK2 (V617F) mutated refractory anemia with ring sideroblasts and thrombocytosis.

Huls G, Mulder AB, Rosati S, van de Loosdrecht AA, Vellenga E, de Wolf JT. Huls G, et al. Blood. 2010 Jul 15;116(2):180-2. doi: 10.1182/blood-2010-01-263087. Epub 2010 Mar 1. Blood. 2010. PMID: 20194893 Free article.

5

Auto-SCT induces a phenotypic shift from CMP to GMP progenitors, reduces clonogenic potential and enhances in vitro and in vivo cycling activity defined by (18)F-FLT PET scanning.

Woolthuis C, Agool A, Olthof S, Slart RH, Huls G, Smid WM, Schuringa JJ, Vellenga E. Woolthuis C, et al. Among authors: huls g. Bone Marrow Transplant. 2011 Jan;46(1):110-5. doi: 10.1038/bmt.2010.75. Epub 2010 Apr 12. Bone Marrow Transplant. 2011. PMID: 20383220

6

Prognostic impact of white blood cell count in intermediate risk acute myeloid leukemia: relevance of mutated NPM1 and FLT3-ITD.

de Jonge HJ, Valk PJ, de Bont ES, Schuringa JJ, Ossenkoppele G, Vellenga E, Huls G. de Jonge HJ, et al. Among authors: huls g. Haematologica. 2011 Sep;96(9):1310-7. doi: 10.3324/haematol.2011.040592. Epub 2011 May 23. Haematologica. 2011. PMID: 21606167 Free PMC article.

7

Aging of hematopoietic stem cells: Intrinsic changes or micro-environmental effects?

Woolthuis CM, de Haan G, Huls G. Woolthuis CM, et al. Among authors: huls g. Curr Opin Immunol. 2011 Aug;23(4):512-7. doi: 10.1016/j.coi.2011.05.006. Epub 2011 Jun 12. Curr Opin Immunol. 2011. PMID: 21664115 Review.

8

Gene expression profiling in the leukemic stem cell-enriched CD34+ fraction identifies target genes that predict prognosis in normal karyotype AML.

de Jonge HJ, Woolthuis CM, Vos AZ, Mulder A, van den Berg E, Kluin PM, van der Weide K, de Bont ES, Huls G, Vellenga E, Schuringa JJ. de Jonge HJ, et al. Among authors: huls g. Leukemia. 2011 Dec;25(12):1825-33. doi: 10.1038/leu.2011.172. Epub 2011 Jul 15. Leukemia. 2011. PMID: 21760593 Clinical Trial.

9

Platelet doubling after the first azacitidine cycle is a promising predictor for response in myelodysplastic syndromes (MDS), chronic myelomonocytic leukaemia (CMML) and acute myeloid leukaemia (AML) patients in the Dutch azacitidine compassionate named patient programme.

van der Helm LH, Alhan C, Wijermans PW, van Marwijk Kooy M, Schaafsma R, Biemond BJ, Beeker A, Hoogendoorn M, van Rees BP, de Weerdt O, Wegman J, Libourel WJ, Luykx-de Bakker SA, Minnema MC, Brouwer RE, Croon-de Boer F, Eefting M, Jie KS, van de Loosdrecht AA, Koedam J, Veeger NJ, Vellenga E, Huls G. van der Helm LH, et al. Among authors: huls g. Br J Haematol. 2011 Dec;155(5):599-606. doi: 10.1111/j.1365-2141.2011.08893.x. Epub 2011 Oct 8. Br J Haematol. 2011. PMID: 21981697 Free article. Clinical Trial.

10

Downregulation of MEIS1 impairs long-term expansion of CD34+ NPM1-mutated acute myeloid leukemia cells.

Woolthuis CM, Han L, Verkaik-Schakel RN, van Gosliga D, Kluin PM, Vellenga E, Schuringa JJ, Huls G. Woolthuis CM, et al. Among authors: huls g. Leukemia. 2012 Apr;26(4):848-53. doi: 10.1038/leu.2011.277. Epub 2011 Oct 11. Leukemia. 2012. PMID: 21986840 No abstract available.

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