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Natural product HTP screening for antibacterial (E.coli 0157:H7) and anti-inflammatory agents in (LPS from E. coli O111:B4) activated macrophages and microglial cells; focus on sepsis.
Mazzio EA, Li N, Bauer D, Mendonca P, Taka E, Darb M, Thomas L, Williams H, Soliman KF. Mazzio EA, et al. Among authors: mendonca p. BMC Complement Altern Med. 2016 Nov 15;16(1):467. doi: 10.1186/s12906-016-1429-x. BMC Complement Altern Med. 2016. PMID: 27846826 Free PMC article.
Thymoquinone increases the expression of neuroprotective proteins while decreasing the expression of pro-inflammatory cytokines and the gene expression NFκB pathway signaling targets in LPS/IFNγ -activated BV-2 microglia cells.
Cobourne-Duval MK, Taka E, Mendonca P, Soliman KFA. Cobourne-Duval MK, et al. Among authors: mendonca p. J Neuroimmunol. 2018 Jul 15;320:87-97. doi: 10.1016/j.jneuroim.2018.04.018. Epub 2018 May 4. J Neuroimmunol. 2018. PMID: 29759145 Free PMC article.
234 results