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Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development.
Christensen KE, Hou W, Bahous RH, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Christensen KE, et al. Am J Clin Nutr. 2016 Nov;104(5):1459-1469. doi: 10.3945/ajcn.116.139519. Epub 2016 Oct 5. Am J Clin Nutr. 2016. PMID: 27707701 Free article.
Control of anterior GRadient 2 (AGR2) dimerization links endoplasmic reticulum proteostasis to inflammation.
Maurel M, Obacz J, Avril T, Ding YP, Papadodima O, Treton X, Daniel F, Pilalis E, Hörberg J, Hou W, Beauchamp MC, Tourneur-Marsille J, Cazals-Hatem D, Sommerova L, Samali A, Tavernier J, Hrstka R, Dupont A, Fessart D, Delom F, Fernandez-Zapico ME, Jansen G, Eriksson LA, Thomas DY, Jerome-Majewska L, Hupp T, Chatziioannou A, Chevet E, Ogier-Denis E. Maurel M, et al. EMBO Mol Med. 2019 Jun;11(6):e10120. doi: 10.15252/emmm.201810120. EMBO Mol Med. 2019. PMID: 31040128 Free PMC article.
49 results