Moore SF - Search Results

1

Phenotype description and response to thrombopoietin receptor agonist in DIAPH1-related disorder.

Westbury SK, Downes K, Burney C, Lozano ML, Obaji SG, Toh CH, Sevivas T, Morgan NV, Erber WN, Kempster C, Moore SF, Thys C, Papadia S, Ouwehand WH; NIHR BioResource–Rare Diseases; Laffan MA, Gomez K, Freson K, Rivera J, Mumford AD. Westbury SK, et al. Among authors: moore sf. Blood Adv. 2018 Sep 25;2(18):2341-2346. doi: 10.1182/bloodadvances.2018020370. Blood Adv. 2018. PMID: 30232087 Free PMC article.

2

Dysfunction of the PI3 kinase/Rap1/integrin α(IIb)β(3) pathway underlies ex vivo platelet hypoactivity in essential thrombocythemia.

Moore SF, Hunter RW, Harper MT, Savage JS, Siddiq S, Westbury SK, Poole AW, Mumford AD, Hers I. Moore SF, et al. Blood. 2013 Feb 14;121(7):1209-19. doi: 10.1182/blood-2012-05-431288. Epub 2012 Dec 13. Blood. 2013. PMID: 23243278 Free article.

3

Chemical degradation of BTK/TEC as a novel approach to inhibit platelet function.

Trory JS, Munkacsi A, Śledź KM, Vautrinot J, Goudswaard LJ, Jackson ML, Heesom KJ, Moore SF, Poole AW, Nabet B, Aggarwal VK, Hers I. Trory JS, et al. Among authors: moore sf. Blood Adv. 2023 May 9;7(9):1692-1696. doi: 10.1182/bloodadvances.2022008466. Blood Adv. 2023. PMID: 36342848 Free PMC article.

4

In-depth PtdIns(3,4,5)P₃ signalosome analysis identifies DAPP1 as a negative regulator of GPVI-driven platelet function.

Durrant TN, Hutchinson JL, Heesom KJ, Anderson KE, Stephens LR, Hawkins PT, Marshall AJ, Moore SF, Hers I. Durrant TN, et al. Among authors: moore sf. Blood Adv. 2017 Jun 13;1(14):918-932. doi: 10.1182/bloodadvances.2017005173. Blood Adv. 2017. PMID: 29242851 Free PMC article.

5

Phosphoinositide 3-kinase p110α negatively regulates thrombopoietin-mediated platelet activation and thrombus formation.

Blair TA, Moore SF, Walsh TG, Hutchinson JL, Durrant TN, Anderson KE, Poole AW, Hers I. Blair TA, et al. Among authors: moore sf. Cell Signal. 2018 Oct;50:111-120. doi: 10.1016/j.cellsig.2018.05.005. Epub 2018 May 21. Cell Signal. 2018. PMID: 29793021

6

Protein kinase C and P2Y12 take center stage in thrombin-mediated activation of mammalian target of rapamycin complex 1 in human platelets.

Moore SF, Hunter RW, Hers I. Moore SF, et al. J Thromb Haemost. 2014 May;12(5):748-60. doi: 10.1111/jth.12552. J Thromb Haemost. 2014. PMID: 24612393 Free PMC article.

7

mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected].

Moore SF, Hunter RW, Hers I. Moore SF, et al. J Biol Chem. 2011 Jul 15;286(28):24553-60. doi: 10.1074/jbc.M110.202341. Epub 2011 May 18. J Biol Chem. 2011. PMID: 21592956 Free PMC article.

8

Phosphoinositide 3-kinases p110α and p110β have differential roles in insulin-like growth factor-1-mediated Akt phosphorylation and platelet priming.

Blair TA, Moore SF, Williams CM, Poole AW, Vanhaesebroeck B, Hers I. Blair TA, et al. Among authors: moore sf. Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1681-8. doi: 10.1161/ATVBAHA.114.303954. Epub 2014 Jun 5. Arterioscler Thromb Vasc Biol. 2014. PMID: 24903091

9

Critical roles for the phosphatidylinositide 3-kinase isoforms p110β and p110γ in thrombopoietin-mediated priming of platelet function.

Moore SF, Smith NR, Blair TA, Durrant TN, Hers I. Moore SF, et al. Sci Rep. 2019 Feb 6;9(1):1468. doi: 10.1038/s41598-018-37012-9. Sci Rep. 2019. PMID: 30728366 Free PMC article.

10

Circulating primers enhance platelet function and induce resistance to antiplatelet therapy.

Blair TA, Moore SF, Hers I. Blair TA, et al. Among authors: moore sf. J Thromb Haemost. 2015 Aug;13(8):1479-93. doi: 10.1111/jth.13022. Epub 2015 Jun 25. J Thromb Haemost. 2015. PMID: 26039631 Free PMC article.

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