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Stiffness-Induced Endothelial DLC-1 Expression Forces Leukocyte Spreading through Stabilization of the ICAM-1 Adhesome.
Schimmel L, van der Stoel M, Rianna C, van Stalborch AM, de Ligt A, Hoogenboezem M, Tol S, van Rijssel J, Szulcek R, Bogaard HJ, Hofmann P, Boon R, Radmacher M, de Waard V, Huveneers S, van Buul JD. Schimmel L, et al. Cell Rep. 2018 Sep 18;24(12):3115-3124. doi: 10.1016/j.celrep.2018.08.045. Cell Rep. 2018. PMID: 30231995 Free article.
Tyrosine-protein kinase Yes controls endothelial junctional plasticity and barrier integrity by regulating VE-cadherin phosphorylation and endocytosis.
Jin Y, Ding Y, Richards M, Kaakinen M, Giese W, Baumann E, Szymborska A, Rosa A, Nordling S, Schimmel L, Akmeriç EB, Pena A, Nwadozi E, Jamalpour M, Holstein K, Sáinz-Jaspeado M, Bernabeu MO, Welsh M, Gordon E, Franco CA, Vestweber D, Eklund L, Gerhardt H, Claesson-Welsh L. Jin Y, et al. Among authors: schimmel l. Nat Cardiovasc Res. 2022 Dec 7;1(12):1156-1173. doi: 10.1038/s44161-022-00172-z. Nat Cardiovasc Res. 2022. PMID: 37936984 Free PMC article.
Leukocyte transendothelial migration: A local affair.
Schimmel L, Heemskerk N, van Buul JD. Schimmel L, et al. Small GTPases. 2017 Jan 2;8(1):1-15. doi: 10.1080/21541248.2016.1197872. Epub 2016 Aug 15. Small GTPases. 2017. PMID: 27715453 Free PMC article. Review.
Endothelial junctional membrane protrusions serve as hotspots for neutrophil transmigration.
Arts JJ, Mahlandt EK, Grönloh ML, Schimmel L, Noordstra I, Gordon E, van Steen AC, Tol S, Walzog B, van Rijssel J, Nolte MA, Postma M, Khuon S, Heddleston JM, Wait E, Chew TL, Winter M, Montanez E, Goedhart J, van Buul JD. Arts JJ, et al. Among authors: schimmel l. Elife. 2021 Aug 25;10:e66074. doi: 10.7554/eLife.66074. Elife. 2021. PMID: 34431475 Free PMC article.
36 results