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Pharmacokinetics, Excretion, and Mass Balance of [14 C]-Batefenterol Following a Single Microtracer Intravenous Dose (Concomitant to an Inhaled Dose) or Oral Dose of Batefenterol in Healthy Men.
Ambery C, Young G, Fuller T, Lazaar AL, Pereira A, Hughes A, Ramsay D, van den Berg F, Daley-Yates P. Ambery C, et al. Among authors: lazaar al. Clin Pharmacol Drug Dev. 2018 Nov;7(8):901-910. doi: 10.1002/cpdd.616. Epub 2018 Sep 19. Clin Pharmacol Drug Dev. 2018. PMID: 30230263 Free PMC article. Clinical Trial.
The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers.
Miller BE, Smart K, Mistry S, Ambery CL, Bloomer JC, Connolly P, Sanderson D, Shreeves T, Smith R, Lazaar AL. Miller BE, et al. Among authors: lazaar al. Eur J Drug Metab Pharmacokinet. 2014 Sep;39(3):173-81. doi: 10.1007/s13318-014-0179-8. Epub 2014 Feb 7. Eur J Drug Metab Pharmacokinet. 2014. PMID: 24504700 Free PMC article. Clinical Trial.
Identification and characterisation of a salt form of Danirixin with reduced pharmacokinetic variability in patient populations.
Bloomer JC, Ambery C, Miller BE, Connolly P, Garden H, Henley N, Hodnett N, Keel S, Kreindler JL, Lloyd RS, Matthews W, Yonchuk J, Lazaar AL. Bloomer JC, et al. Among authors: lazaar al. Eur J Pharm Biopharm. 2017 Aug;117:224-231. doi: 10.1016/j.ejpb.2017.03.023. Epub 2017 Apr 3. Eur J Pharm Biopharm. 2017. PMID: 28385615 Clinical Trial.
Effect of the CXCR2 antagonist danirixin on symptoms and health status in COPD.
Lazaar AL, Miller BE, Tabberer M, Yonchuk J, Leidy N, Ambery C, Bloomer J, Watz H, Tal-Singer R. Lazaar AL, et al. Eur Respir J. 2018 Oct 4;52(4):1801020. doi: 10.1183/13993003.01020-2018. Print 2018 Oct. Eur Respir J. 2018. PMID: 30139779 Free article. Clinical Trial. No abstract available.
55 results