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Deep Learning and Pathomics Analyses Reveal Cell Nuclei as Important Features for Mutation Prediction of BRAF-Mutated Melanomas.
Kim RH, Nomikou S, Coudray N, Jour G, Dawood Z, Hong R, Esteva E, Sakellaropoulos T, Donnelly D, Moran U, Hatzimemos A, Weber JS, Razavian N, Aifantis I, Fenyo D, Snuderl M, Shapiro R, Berman RS, Osman I, Tsirigos A. Kim RH, et al. Among authors: sakellaropoulos t. J Invest Dermatol. 2022 Jun;142(6):1650-1658.e6. doi: 10.1016/j.jid.2021.09.034. Epub 2021 Oct 30. J Invest Dermatol. 2022. PMID: 34757067 Free PMC article.
A Deep Learning Framework for Predicting Response to Therapy in Cancer.
Sakellaropoulos T, Vougas K, Narang S, Koinis F, Kotsinas A, Polyzos A, Moss TJ, Piha-Paul S, Zhou H, Kardala E, Damianidou E, Alexopoulos LG, Aifantis I, Townsend PA, Panayiotidis MI, Sfikakis P, Bartek J, Fitzgerald RC, Thanos D, Mills Shaw KR, Petty R, Tsirigos A, Gorgoulis VG. Sakellaropoulos T, et al. Cell Rep. 2019 Dec 10;29(11):3367-3373.e4. doi: 10.1016/j.celrep.2019.11.017. Cell Rep. 2019. PMID: 31825821 Free article.
Machine learning and data mining frameworks for predicting drug response in cancer: An overview and a novel in silico screening process based on association rule mining.
Vougas K, Sakellaropoulos T, Kotsinas A, Foukas GP, Ntargaras A, Koinis F, Polyzos A, Myrianthopoulos V, Zhou H, Narang S, Georgoulias V, Alexopoulos L, Aifantis I, Townsend PA, Sfikakis P, Fitzgerald R, Thanos D, Bartek J, Petty R, Tsirigos A, Gorgoulis VG. Vougas K, et al. Among authors: sakellaropoulos t. Pharmacol Ther. 2019 Nov;203:107395. doi: 10.1016/j.pharmthera.2019.107395. Epub 2019 Jul 30. Pharmacol Ther. 2019. PMID: 31374225 Review.
H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization.
Pelham-Webb B, Polyzos A, Wojenski L, Kloetgen A, Li J, Di Giammartino DC, Sakellaropoulos T, Tsirigos A, Core L, Apostolou E. Pelham-Webb B, et al. Among authors: sakellaropoulos t. Mol Cell. 2021 Apr 15;81(8):1732-1748.e8. doi: 10.1016/j.molcel.2021.02.032. Epub 2021 Mar 16. Mol Cell. 2021. PMID: 33730542 Free PMC article.
Targeting Mitochondrial Structure Sensitizes Acute Myeloid Leukemia to Venetoclax Treatment.
Chen X, Glytsou C, Zhou H, Narang S, Reyna DE, Lopez A, Sakellaropoulos T, Gong Y, Kloetgen A, Yap YS, Wang E, Gavathiotis E, Tsirigos A, Tibes R, Aifantis I. Chen X, et al. Among authors: sakellaropoulos t. Cancer Discov. 2019 Jul;9(7):890-909. doi: 10.1158/2159-8290.CD-19-0117. Epub 2019 May 2. Cancer Discov. 2019. PMID: 31048321 Free PMC article.
Non-lethal proteasome inhibition activates pro-tumorigenic pathways in multiple myeloma cells.
Skorda A, Sklirou AD, Sakellaropoulos T, Gianniou DD, Kastritis E, Terpos E, Tsitsilonis OE, Florea BI, Overkleeft HS, Dimopoulos MA, Alexopoulos LG, Trougakos IP. Skorda A, et al. Among authors: sakellaropoulos t. J Cell Mol Med. 2019 Dec;23(12):8010-8018. doi: 10.1111/jcmm.14653. Epub 2019 Sep 30. J Cell Mol Med. 2019. PMID: 31568628 Free PMC article.
33 results