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De novo mutations in MSL3 cause an X-linked syndrome marked by impaired histone H4 lysine 16 acetylation.
Basilicata MF, Bruel AL, Semplicio G, Valsecchi CIK, Aktaş T, Duffourd Y, Rumpf T, Morton J, Bache I, Szymanski WG, Gilissen C, Vanakker O, Õunap K, Mittler G, van der Burgt I, El Chehadeh S, Cho MT, Pfundt R, Tan TY, Kirchhoff M, Menten B, Vergult S, Lindstrom K, Reis A, Johnson DS, Fryer A, McKay V; DDD Study; Fisher RB, Thauvin-Robinet C, Francis D, Roscioli T, Pajusalu S, Radtke K, Ganesh J, Brunner HG, Wilson M, Faivre L, Kalscheuer VM, Thevenon J, Akhtar A. Basilicata MF, et al. Among authors: mittler g. Nat Genet. 2018 Oct;50(10):1442-1451. doi: 10.1038/s41588-018-0220-y. Epub 2018 Sep 17. Nat Genet. 2018. PMID: 30224647 Free PMC article.
Functional interplay between MSL1 and CDK7 controls RNA polymerase II Ser5 phosphorylation.
Chlamydas S, Holz H, Samata M, Chelmicki T, Georgiev P, Pelechano V, Dündar F, Dasmeh P, Mittler G, Cadete FT, Ramírez F, Conrad T, Wei W, Raja S, Manke T, Luscombe NM, Steinmetz LM, Akhtar A. Chlamydas S, et al. Among authors: mittler g. Nat Struct Mol Biol. 2016 Jun;23(6):580-9. doi: 10.1038/nsmb.3233. Epub 2016 May 16. Nat Struct Mol Biol. 2016. PMID: 27183194
Histone propionylation is a mark of active chromatin.
Kebede AF, Nieborak A, Shahidian LZ, Le Gras S, Richter F, Gómez DA, Baltissen MP, Meszaros G, Magliarelli HF, Taudt A, Margueron R, Colomé-Tatché M, Ricci R, Daujat S, Vermeulen M, Mittler G, Schneider R. Kebede AF, et al. Among authors: mittler g. Nat Struct Mol Biol. 2017 Dec;24(12):1048-1056. doi: 10.1038/nsmb.3490. Epub 2017 Oct 23. Nat Struct Mol Biol. 2017. PMID: 29058708
The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.
Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A. Karoutas A, et al. Among authors: mittler g. Nat Cell Biol. 2019 Oct;21(10):1248-1260. doi: 10.1038/s41556-019-0397-z. Epub 2019 Oct 1. Nat Cell Biol. 2019. PMID: 31576060
Author Correction: The NSL complex maintains nuclear architecture stability via lamin A/C acetylation.
Karoutas A, Szymanski W, Rausch T, Guhathakurta S, Rog-Zielinska EA, Peyronnet R, Seyfferth J, Chen HR, de Leeuw R, Herquel B, Kimura H, Mittler G, Kohl P, Medalia O, Korbel JO, Akhtar A. Karoutas A, et al. Among authors: mittler g. Nat Cell Biol. 2023 Apr;25(4):626. doi: 10.1038/s41556-023-01106-y. Nat Cell Biol. 2023. PMID: 36849559 No abstract available.
62 results