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NOTCH1 Represses MCL-1 Levels in GSI-resistant T-ALL, Making them Susceptible to ABT-263.
Dastur A, Choi A, Costa C, Yin X, Williams A, McClanaghan J, Greenberg M, Roderick J, Patel NU, Boisvert J, McDermott U, Garnett MJ, Almenara J, Grant S, Rizzo K, Engelman JA, Kelliher M, Faber AC, Benes CH. Dastur A, et al. Among authors: williams a. Clin Cancer Res. 2019 Jan 1;25(1):312-324. doi: 10.1158/1078-0432.CCR-18-0867. Epub 2018 Sep 17. Clin Cancer Res. 2019. PMID: 30224339 Free PMC article.
Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer.
Raoof S, Mulford IJ, Frisco-Cabanos H, Nangia V, Timonina D, Labrot E, Hafeez N, Bilton SJ, Drier Y, Ji F, Greenberg M, Williams A, Kattermann K, Damon L, Sovath S, Rakiec DP, Korn JM, Ruddy DA, Benes CH, Hammerman PS, Piotrowska Z, Sequist LV, Niederst MJ, Barretina J, Engelman JA, Hata AN. Raoof S, et al. Among authors: williams a. Oncogene. 2019 Sep;38(37):6399-6413. doi: 10.1038/s41388-019-0887-2. Epub 2019 Jul 19. Oncogene. 2019. PMID: 31324888 Free PMC article.
Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms.
Hu H, Piotrowska Z, Hare PJ, Chen H, Mulvey HE, Mayfield A, Noeen S, Kattermann K, Greenberg M, Williams A, Riley AK, Wilson JJ, Mao YQ, Huang RP, Banwait MK, Ho J, Crowther GS, Hariri LP, Heist RS, Kodack DP, Pinello L, Shaw AT, Mino-Kenudson M, Hata AN, Sequist LV, Benes CH, Niederst MJ, Engelman JA. Hu H, et al. Among authors: williams a. Cancer Cell. 2021 Nov 8;39(11):1531-1547.e10. doi: 10.1016/j.ccell.2021.09.003. Epub 2021 Oct 7. Cancer Cell. 2021. PMID: 34624218 Free PMC article.
Paving the way for quality assured, decentralised point-of-care testing for infectious disease in primary care - Real world lessons from remote Australia.
Applegate TL, Causer LM, Gow I, Alternetti N, Anderson L, Borgnolo B, Cooney L, Cunningham P, Fernando M, Hengel B, Huang RL, Kayago K, King JM, Lew HJ, Martinello M, Milic M, Miller K, O'Connor S, Patel P, Phillips E, Rawlinson W, Sharma A, Shephard MDS, Tangey A, Smith K, Williams AL, Andrewartha K, Guy R, Matthews SJ. Applegate TL, et al. Among authors: williams al. Expert Rev Mol Diagn. 2024 Dec 24:1-14. doi: 10.1080/14737159.2024.2403091. Online ahead of print. Expert Rev Mol Diagn. 2024. PMID: 39719681 Review.
Targeted degradation of oncogenic KRASG12V triggers antitumor immunity in lung cancer models.
Li D, Geng K, Hao Y, Gu J, Kumar S, Olson AT, Kuismi CC, Kim HM, Pan Y, Sherman F, Williams AM, Li Y, Li F, Chen T, Thakurdin C, Ranieri M, Meynardie M, Levin DS, Stephens J, Chafitz A, Chen J, Donald-Paladino MS, Powell JM, Zhang ZY, Chen W, Ploszaj M, Han H, Gu S, Zhang T, Hu B, Nacev BA, Kaiza ME, Berger AH, Wang X, Li J, Sun X, Liu Y, Zhang X, Bruno TC, Gray NS, Nabet B, Wong KK, Zhang H. Li D, et al. Among authors: williams am. J Clin Invest. 2024 Dec 24:e174249. doi: 10.1172/JCI174249. Online ahead of print. J Clin Invest. 2024. PMID: 39718828 Free article.
snRNA-seq stratifies multiple sclerosis patients into distinct white matter glial responses.
Macnair W, Calini D, Agirre E, Bryois J, Jäkel S, Smith RS, Kukanja P, Stokar-Regenscheit N, Ott V, Foo LC, Collin L, Schippling S, Urich E, Nutma E, Marzin M, Ansaloni F, Amor S, Magliozzi R, Heidari E, Robinson MD, Ffrench-Constant C, Castelo-Branco G, Williams A, Malhotra D. Macnair W, et al. Among authors: williams a. Neuron. 2024 Dec 20:S0896-6273(24)00873-0. doi: 10.1016/j.neuron.2024.11.016. Online ahead of print. Neuron. 2024. PMID: 39708806 Free article.
Tracing the transmission of carbapenem-resistant Enterobacterales at the patient: ward environmental nexus.
Elton L, Williams A, Ali S, Heaphy J, Pang V, Commins L, O'Brien C, Yetiş Ö, Caine E, Ward I, Muzslay M, Yui S, Karia K, Shore E, Rofael S, Mack DJF, McHugh TD, Wey EQ. Elton L, et al. Among authors: williams a. Ann Clin Microbiol Antimicrob. 2024 Dec 20;23(1):108. doi: 10.1186/s12941-024-00762-8. Ann Clin Microbiol Antimicrob. 2024. PMID: 39707381 Free PMC article.
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