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Twenty-Year Progression Rate to Clinical Onset According to Autoantibody Profile, Age, and HLA-DQ Genotype in a Registry-Based Group of Children and Adults With a First-Degree Relative With Type 1 Diabetes.
Gorus FK, Balti EV, Messaaoui A, Demeester S, Van Dalem A, Costa O, Dorchy H, Mathieu C, Van Gaal L, Keymeulen B, Pipeleers DG, Weets I; Belgian Diabetes Registry. Gorus FK, et al. Diabetes Care. 2017 Aug;40(8):1065-1072. doi: 10.2337/dc16-2228. Diabetes Care. 2017. PMID: 28701370
Accelerated Progression to Type 1 Diabetes in the Presence of HLA-A*24 and -B*18 Is Restricted to Multiple Islet Autoantibody-Positive Individuals With Distinct HLA-DQ and Autoantibody Risk Profiles.
Balke EM, Balti EV, Van der Auwera B, Weets I, Costa O, Demeester S, Abrams P, Casteels K, Coeckelberghs M, Tenoutasse S, Keymeulen B, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Balke EM, et al. Diabetes Care. 2018 May;41(5):1076-1083. doi: 10.2337/dc17-2462. Epub 2018 Mar 15. Diabetes Care. 2018. PMID: 29545461
Screening for insulinoma antigen 2 and zinc transporter 8 autoantibodies: a cost-effective and age-independent strategy to identify rapid progressors to clinical onset among relatives of type 1 diabetic patients.
Gorus FK, Balti EV, Vermeulen I, Demeester S, Van Dalem A, Costa O, Dorchy H, Tenoutasse S, Mouraux T, De Block C, Gillard P, Decochez K, Wenzlau JM, Hutton JC, Pipeleers DG, Weets I; Belgian Diabetes Registry. Gorus FK, et al. Clin Exp Immunol. 2013 Jan;171(1):82-90. doi: 10.1111/j.1365-2249.2012.04675.x. Clin Exp Immunol. 2013. PMID: 23199327 Free PMC article.
An important minority of prediabetic first-degree relatives of type 1 diabetic patients derives from seroconversion to persistent autoantibody positivity after 10 years of age.
Vermeulen I, Weets I, Costa O, Asanghanwa M, Verhaeghen K, Decochez K, Ruige J, Casteels K, Wenzlau J, Hutton JC, Pipeleers DG, Gorus FK; Belgian Diabetes Registry. Vermeulen I, et al. Diabetologia. 2012 Feb;55(2):413-20. doi: 10.1007/s00125-011-2376-1. Epub 2011 Nov 18. Diabetologia. 2012. PMID: 22095238 Free PMC article.
Potential of UCHL1 as biomarker for destruction of pancreatic beta cells.
Brackeva B, De Punt V, Kramer G, Costa O, Verhaeghen K, Stangé G, Sadones J, Xavier C, Aerts JM, Gorus FK, Martens GA. Brackeva B, et al. J Proteomics. 2015 Mar 18;117:156-67. doi: 10.1016/j.jprot.2015.01.009. Epub 2015 Jan 29. J Proteomics. 2015. PMID: 25638021
108,428 results
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