Kelly JM - Search Results

1

Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.

Adjogatse E, Erskine P, Wells SA, Kelly JM, Wilden JD, Chan AWE, Selwood D, Coker A, Wood S, Cooper JB. Adjogatse E, et al. Among authors: kelly jm. Acta Crystallogr D Struct Biol. 2018 Sep 1;74(Pt 9):861-876. doi: 10.1107/S2059798318009208. Epub 2018 Sep 3. Acta Crystallogr D Struct Biol. 2018. PMID: 30198897 Free article.

2

Deletion of the Trypanosoma brucei superoxide dismutase gene sodb1 increases sensitivity to nifurtimox and benznidazole.

Prathalingham SR, Wilkinson SR, Horn D, Kelly JM. Prathalingham SR, et al. Among authors: kelly jm. Antimicrob Agents Chemother. 2007 Feb;51(2):755-8. doi: 10.1128/AAC.01360-06. Epub 2006 Dec 4. Antimicrob Agents Chemother. 2007. PMID: 17145786 Free PMC article.

3

Centromere-associated topoisomerase activity in bloodstream form Trypanosoma brucei.

Obado SO, Bot C, Echeverry MC, Bayona JC, Alvarez VE, Taylor MC, Kelly JM. Obado SO, et al. Among authors: kelly jm. Nucleic Acids Res. 2011 Feb;39(3):1023-33. doi: 10.1093/nar/gkq839. Epub 2010 Sep 22. Nucleic Acids Res. 2011. PMID: 20864447 Free PMC article.

4

Inhibitors of human histone deacetylase with potent activity against the African trypanosome Trypanosoma brucei.

Kelly JM, Taylor MC, Horn D, Loza E, Kalvinsh I, Björkling F. Kelly JM, et al. Bioorg Med Chem Lett. 2012 Mar 1;22(5):1886-90. doi: 10.1016/j.bmcl.2012.01.072. Epub 2012 Jan 28. Bioorg Med Chem Lett. 2012. PMID: 22326398 Free PMC article.

5

Novel 2,6-diketopiperazine-derived acetohydroxamic acids as promising anti-Trypanosoma brucei agents.

Fytas G, Zoidis G, Taylor MC, Kelly JM, Tsatsaroni A, Tsotinis A. Fytas G, et al. Among authors: kelly jm. Future Med Chem. 2019 Jun;11(11):1259-1266. doi: 10.4155/fmc-2018-0599. Epub 2019 Jun 4. Future Med Chem. 2019. PMID: 31161793

6

In vitro and in vivo activities of aminoadamantane and aminoalkylcyclohexane derivatives against Trypanosoma brucei.

Kelly JM, Quack G, Miles MM. Kelly JM, et al. Antimicrob Agents Chemother. 2001 May;45(5):1360-6. doi: 10.1128/AAC.45.5.1360-1366.2001. Antimicrob Agents Chemother. 2001. PMID: 11302796 Free PMC article.

7

The role of glutathione peroxidases in trypanosomatids.

Wilkinson SR, Kelly JM. Wilkinson SR, et al. Among authors: kelly jm. Biol Chem. 2003 Apr;384(4):517-25. doi: 10.1515/BC.2003.060. Biol Chem. 2003. PMID: 12751782 Review.

8

RNA interference identifies two hydroperoxide metabolizing enzymes that are essential to the bloodstream form of the african trypanosome.

Wilkinson SR, Horn D, Prathalingam SR, Kelly JM. Wilkinson SR, et al. Among authors: kelly jm. J Biol Chem. 2003 Aug 22;278(34):31640-6. doi: 10.1074/jbc.M303035200. Epub 2003 Jun 5. J Biol Chem. 2003. PMID: 12791697 Free article.

9

Functional characterisation of the iron superoxide dismutase gene repertoire in Trypanosoma brucei.

Wilkinson SR, Prathalingam SR, Taylor MC, Ahmed A, Horn D, Kelly JM. Wilkinson SR, et al. Among authors: kelly jm. Free Radic Biol Med. 2006 Jan 15;40(2):198-209. doi: 10.1016/j.freeradbiomed.2005.06.022. Epub 2005 Aug 18. Free Radic Biol Med. 2006. PMID: 16413403

10

The terminal step in vitamin C biosynthesis in Trypanosoma cruzi is mediated by a FMN-dependent galactonolactone oxidase.

Logan FJ, Taylor MC, Wilkinson SR, Kaur H, Kelly JM. Logan FJ, et al. Among authors: kelly jm. Biochem J. 2007 Nov 1;407(3):419-26. doi: 10.1042/BJ20070766. Biochem J. 2007. PMID: 17627608 Free PMC article.

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