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( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.
Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP. Liu Y, et al. Among authors: zvonok n. J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21. J Med Chem. 2018. PMID: 30196704
Oxa-adamantyl cannabinoids.
Ho TC, Tius MA, Nikas SP, Tran NK, Tong F, Zhou H, Zvonok N, Makriyannis A. Ho TC, et al. Among authors: zvonok n. Bioorg Med Chem Lett. 2021 Apr 15;38:127882. doi: 10.1016/j.bmcl.2021.127882. Epub 2021 Feb 24. Bioorg Med Chem Lett. 2021. PMID: 33636308
Improved cyclobutyl nabilone analogs as potent CB1 receptor agonists.
Papanastasiou IP, Georgiadis MO, Iliopoulos-Tsoutsouvas C, Paronis CA, Brust CA, Tran NK, Ji L, Ma X, Wood JT, Zvonok N, Tong F, Bohn LM, Nikas SP, Makriyannis A. Papanastasiou IP, et al. Among authors: zvonok n. Eur J Med Chem. 2022 Feb 15;230:114027. doi: 10.1016/j.ejmech.2021.114027. Epub 2021 Dec 27. Eur J Med Chem. 2022. PMID: 35051750
Sulfonyl fluoride inhibitors of fatty acid amide hydrolase.
Alapafuja SO, Nikas SP, Bharathan IT, Shukla VG, Nasr ML, Bowman AL, Zvonok N, Li J, Shi X, Engen JR, Makriyannis A. Alapafuja SO, et al. Among authors: zvonok n. J Med Chem. 2012 Nov 26;55(22):10074-89. doi: 10.1021/jm301205j. Epub 2012 Nov 2. J Med Chem. 2012. PMID: 23083016 Free PMC article.
Molecular-interaction and signaling profiles of AM3677, a novel covalent agonist selective for the cannabinoid 1 receptor.
Janero DR, Yaddanapudi S, Zvonok N, Subramanian KV, Shukla VG, Stahl E, Zhou L, Hurst D, Wager-Miller J, Bohn LM, Reggio PH, Mackie K, Makriyannis A. Janero DR, et al. Among authors: zvonok n. ACS Chem Neurosci. 2015 Aug 19;6(8):1400-10. doi: 10.1021/acschemneuro.5b00090. Epub 2015 May 29. ACS Chem Neurosci. 2015. PMID: 25978068 Free PMC article.
Novel Functionalized Cannabinoid Receptor Probes: Development of Exceptionally Potent Agonists.
Jiang S, Iliopoulos-Tsoutsouvas C, Tong F, Brust CA, Keenan CM, Raghav JG, Hua T, Wu S, Ho JH, Wu Y, Grim TW, Zvonok N, Thakur GA, Liu ZJ, Sharkey KA, Bohn LM, Nikas SP, Makriyannis A. Jiang S, et al. Among authors: zvonok n. J Med Chem. 2021 Apr 8;64(7):3870-3884. doi: 10.1021/acs.jmedchem.0c02053. Epub 2021 Mar 24. J Med Chem. 2021. PMID: 33761251
Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s).
Kulkarni PM, Kulkarni AR, Korde A, Tichkule RB, Laprairie RB, Denovan-Wright EM, Zhou H, Janero DR, Zvonok N, Makriyannis A, Cascio MG, Pertwee RG, Thakur GA. Kulkarni PM, et al. Among authors: zvonok n. J Med Chem. 2016 Jan 14;59(1):44-60. doi: 10.1021/acs.jmedchem.5b01303. Epub 2015 Nov 28. J Med Chem. 2016. PMID: 26529344 Free PMC article.
40 results