Makriyannis A - Search Results

1

( R)- N-(1-Methyl-2-hydroxyethyl)-13-( S)-methyl-arachidonamide (AMG315): A Novel Chiral Potent Endocannabinoid Ligand with Stability to Metabolizing Enzymes.

Liu Y, Ji L, Eno M, Kudalkar S, Li AL, Schimpgen M, Benchama O, Morales P, Xu S, Hurst D, Wu S, Mohammad KA, Wood JT, Zvonok N, Papahatjis DP, Zhou H, Honrao C, Mackie K, Reggio P, Hohmann AG, Marnett LJ, Makriyannis A, Nikas SP. Liu Y, et al. Among authors: makriyannis a. J Med Chem. 2018 Oct 11;61(19):8639-8657. doi: 10.1021/acs.jmedchem.8b00611. Epub 2018 Sep 21. J Med Chem. 2018. PMID: 30196704

2

Studies on the thermotropic effects of cannabinoids on phosphatidylcholine bilayers using differential scanning calorimetry and small angle X-ray diffraction.

Mavromoustakos T, Theodoropoulou E, Papahatjis D, Kourouli T, Yang DP, Trumbore M, Makriyannis A. Mavromoustakos T, et al. Among authors: makriyannis a. Biochim Biophys Acta. 1996 Jun 11;1281(2):235-44. doi: 10.1016/0005-2736(96)00027-2. Biochim Biophys Acta. 1996. PMID: 8664323 Free article.

3

Head group analogs of arachidonylethanolamide, the endogenous cannabinoid ligand.

Khanolkar AD, Abadji V, Lin S, Hill WA, Taha G, Abouzid K, Meng Z, Fan P, Makriyannis A. Khanolkar AD, et al. Among authors: makriyannis a. J Med Chem. 1996 Oct 25;39(22):4515-9. doi: 10.1021/jm960152y. J Med Chem. 1996. PMID: 8893848

4

Pharmacophoric requirements for cannabinoid side chains: multiple bond and C1'-substituted delta 8-tetrahydrocannabinols.

Papahatjis DP, Kourouli T, Abadji V, Goutopoulos A, Makriyannis A. Papahatjis DP, et al. Among authors: makriyannis a. J Med Chem. 1998 Mar 26;41(7):1195-200. doi: 10.1021/jm970277i. J Med Chem. 1998. PMID: 9544219

5

Novel analogues of arachidonylethanolamide (anandamide): affinities for the CB1 and CB2 cannabinoid receptors and metabolic stability.

Lin S, Khanolkar AD, Fan P, Goutopoulos A, Qin C, Papahadjis D, Makriyannis A. Lin S, et al. Among authors: makriyannis a. J Med Chem. 1998 Dec 31;41(27):5353-61. doi: 10.1021/jm970257g. J Med Chem. 1998. PMID: 9876105

6

Structure-activity relationships of pyrazole derivatives as cannabinoid receptor antagonists.

Lan R, Liu Q, Fan P, Lin S, Fernando SR, McCallion D, Pertwee R, Makriyannis A. Lan R, et al. Among authors: makriyannis a. J Med Chem. 1999 Feb 25;42(4):769-76. doi: 10.1021/jm980363y. J Med Chem. 1999. PMID: 10052983

7

Stereochemical selectivity of methanandamides for the CB1 and CB2 cannabinoid receptors and their metabolic stability.

Goutopoulos A, Fan P, Khanolkar AD, Xie XQ, Lin S, Makriyannis A. Goutopoulos A, et al. Among authors: makriyannis a. Bioorg Med Chem. 2001 Jul;9(7):1673-84. doi: 10.1016/s0968-0896(01)00088-8. Bioorg Med Chem. 2001. PMID: 11425567

8

Novel 1',1'-chain substituted Delta(8)-tetrahydrocannabinols.

Papahatjis DP, Nikas SP, Andreou T, Makriyannis A. Papahatjis DP, et al. Among authors: makriyannis a. Bioorg Med Chem Lett. 2002 Dec 16;12(24):3583-6. doi: 10.1016/s0960-894x(02)00785-0. Bioorg Med Chem Lett. 2002. PMID: 12443781

9

Selective activation of cannabinoid CB(2) receptors suppresses spinal fos protein expression and pain behavior in a rat model of inflammation.

Nackley AG, Makriyannis A, Hohmann AG. Nackley AG, et al. Among authors: makriyannis a. Neuroscience. 2003;119(3):747-57. doi: 10.1016/s0306-4522(03)00126-x. Neuroscience. 2003. PMID: 12809695

10

Pharmacophoric requirements for the cannabinoid side chain. Probing the cannabinoid receptor subsite at C1'.

Papahatjis DP, Nikas SP, Kourouli T, Chari R, Xu W, Pertwee RG, Makriyannis A. Papahatjis DP, et al. Among authors: makriyannis a. J Med Chem. 2003 Jul 17;46(15):3221-9. doi: 10.1021/jm020558c. J Med Chem. 2003. PMID: 12852753

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