Arafa RK - Search Results

1

New 1-phthalazinone Scaffold based Compounds: Design, Synthesis, Cytotoxicity and Protein Kinase Inhibition Activity.

Abo-Elmagd NE, George RF, Ezzat MA, Arafa RK. Abo-Elmagd NE, et al. Among authors: arafa rk. Mini Rev Med Chem. 2018;18(20):1759-1774. doi: 10.2174/1389557518666180903153254. Mini Rev Med Chem. 2018. PMID: 30179133

2

Design and synthesis of novel benzopyran-2-one derivatives of expected antimicrobial activity through DNA gyrase-B inhibition.

Hassan GS, Farag NA, Hegazy GH, Arafa RK. Hassan GS, et al. Among authors: arafa rk. Arch Pharm (Weinheim). 2008 Nov;341(11):725-33. doi: 10.1002/ardp.200700266. Arch Pharm (Weinheim). 2008. PMID: 18973170

3

Molecular modeling study and synthesis of novel dicationic flexible triaryl guanidines and imidamides as antiprotozoal agents.

Arafa RK, Wenzler T, Brun R, Chai Y, Wilson WD. Arafa RK, et al. Eur J Med Chem. 2011 Dec;46(12):5852-60. doi: 10.1016/j.ejmech.2011.09.047. Epub 2011 Oct 2. Eur J Med Chem. 2011. PMID: 22005186

4

Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents.

Arafa RK, Hegazy GH, Piazza GA, Abadi AH. Arafa RK, et al. Eur J Med Chem. 2013 May;63:826-32. doi: 10.1016/j.ejmech.2013.03.008. Epub 2013 Mar 16. Eur J Med Chem. 2013. PMID: 23584545

5

Design, synthesis and molecular docking of novel N,N-dimethylbenzenesulfonamide derivatives as potential antiproliferative agents.

Bashandy MS, Alsaid MS, Arafa RK, Ghorab MM. Bashandy MS, et al. Among authors: arafa rk. J Enzyme Inhib Med Chem. 2014 Oct;29(5):619-27. doi: 10.3109/14756366.2013.833197. Epub 2013 Oct 3. J Enzyme Inhib Med Chem. 2014. PMID: 24090422 Free article.

6

Novel heterocyclic-fused pyrimidine derivatives: synthesis, molecular modeling and pharmacological screening.

Arafa RK, Nour MS, El-Sayed NA. Arafa RK, et al. Eur J Med Chem. 2013 Nov;69:498-507. doi: 10.1016/j.ejmech.2013.08.042. Epub 2013 Sep 12. Eur J Med Chem. 2013. PMID: 24090920

7

Design, synthesis and structure-activity relationship of novel semi-synthetic flavonoids as antiproliferative agents.

Ragab FA, Yahya TA, El-Naa MM, Arafa RK. Ragab FA, et al. Among authors: arafa rk. Eur J Med Chem. 2014 Jul 23;82:506-20. doi: 10.1016/j.ejmech.2014.06.007. Epub 2014 Jun 5. Eur J Med Chem. 2014. PMID: 24937184

8

Novel sulfonamides bearing pyrrole and pyrrolopyrimidine moieties as carbonic anhydrase inhibitors: Synthesis, cytotoxic activity and molecular modeling.

Ghorab MM, Ceruso M, Alsaid MS, Nissan YM, Arafa RK, Supuran CT. Ghorab MM, et al. Among authors: arafa rk. Eur J Med Chem. 2014 Nov 24;87:186-96. doi: 10.1016/j.ejmech.2014.09.059. Epub 2014 Sep 19. Eur J Med Chem. 2014. PMID: 25255434

9

Novel Benzo[d]imidazole-based Heterocycles as Broad Spectrum Anti-viral Agents: Design, Synthesis and Exploration of Molecular Basis of Action.

Eldebss TM, Farag AM, Abdulla MM, Arafa RK. Eldebss TM, et al. Among authors: arafa rk. Mini Rev Med Chem. 2016;16(1):67-83. doi: 10.2174/138955751601151029115533. Mini Rev Med Chem. 2016. PMID: 26527409

10

Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines.

Youssef MM, Arafa RK, Ismail MA. Youssef MM, et al. Among authors: arafa rk. Drug Des Devel Ther. 2016 Mar 11;10:1133-46. doi: 10.2147/DDDT.S102128. eCollection 2016. Drug Des Devel Ther. 2016. PMID: 27042005 Free PMC article.

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