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Perforin is a novel immune regulator of obesity-related insulin resistance.
Revelo XS, Tsai S, Lei H, Luck H, Ghazarian M, Tsui H, Shi SY, Schroer S, Luk CT, Lin GH, Mak TW, Woo M, Winer S, Winer DA. Revelo XS, et al. Among authors: lei h. Diabetes. 2015 Jan;64(1):90-103. doi: 10.2337/db13-1524. Epub 2014 Jul 21. Diabetes. 2015. PMID: 25048196
Regulation of obesity-related insulin resistance with gut anti-inflammatory agents.
Luck H, Tsai S, Chung J, Clemente-Casares X, Ghazarian M, Revelo XS, Lei H, Luk CT, Shi SY, Surendra A, Copeland JK, Ahn J, Prescott D, Rasmussen BA, Chng MH, Engleman EG, Girardin SE, Lam TK, Croitoru K, Dunn S, Philpott DJ, Guttman DS, Woo M, Winer S, Winer DA. Luck H, et al. Among authors: lei h. Cell Metab. 2015 Apr 7;21(4):527-42. doi: 10.1016/j.cmet.2015.03.001. Cell Metab. 2015. PMID: 25863246 Free article.
Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.
Revelo XS, Ghazarian M, Chng MH, Luck H, Kim JH, Zeng K, Shi SY, Tsai S, Lei H, Kenkel J, Liu CL, Tangsombatvisit S, Tsui H, Sima C, Xiao C, Shen L, Li X, Jin T, Lewis GF, Woo M, Utz PJ, Glogauer M, Engleman E, Winer S, Winer DA. Revelo XS, et al. Among authors: lei h. Cell Rep. 2016 Jul 19;16(3):717-30. doi: 10.1016/j.celrep.2016.06.024. Epub 2016 Jun 30. Cell Rep. 2016. PMID: 27373163 Free PMC article.
Type I Interferon Responses Drive Intrahepatic T cells to Promote Metabolic Syndrome.
Ghazarian M, Revelo XS, Nøhr MK, Luck H, Zeng K, Lei H, Tsai S, Schroer SA, Park YJ, Chng MHY, Shen L, D'Angelo JA, Horton P, Chapman WC, Brockmeier D, Woo M, Engleman EG, Adeyi O, Hirano N, Jin T, Gehring AJ, Winer S, Winer DA. Ghazarian M, et al. Among authors: lei h. Sci Immunol. 2017 Apr 21;2(10):eaai7616. doi: 10.1126/sciimmunol.aai7616. Sci Immunol. 2017. PMID: 28567448 Free PMC article.
Aryl hydrocarbon receptor agonist indigo protects against obesity-related insulin resistance through modulation of intestinal and metabolic tissue immunity.
Lin YH, Luck H, Khan S, Schneeberger PHH, Tsai S, Clemente-Casares X, Lei H, Leu YL, Chan YT, Chen HY, Yang SH, Coburn B, Winer S, Winer DA. Lin YH, et al. Among authors: lei h. Int J Obes (Lond). 2019 Dec;43(12):2407-2421. doi: 10.1038/s41366-019-0340-1. Epub 2019 Apr 3. Int J Obes (Lond). 2019. PMID: 30944419 Free PMC article.
Gut-associated IgA+ immune cells regulate obesity-related insulin resistance.
Luck H, Khan S, Kim JH, Copeland JK, Revelo XS, Tsai S, Chakraborty M, Cheng K, Tao Chan Y, Nøhr MK, Clemente-Casares X, Perry MC, Ghazarian M, Lei H, Lin YH, Coburn B, Okrainec A, Jackson T, Poutanen S, Gaisano H, Allard JP, Guttman DS, Conner ME, Winer S, Winer DA. Luck H, et al. Among authors: lei h. Nat Commun. 2019 Aug 13;10(1):3650. doi: 10.1038/s41467-019-11370-y. Nat Commun. 2019. PMID: 31409776 Free PMC article.
Mechanical Stiffness Controls Dendritic Cell Metabolism and Function.
Chakraborty M, Chu K, Shrestha A, Revelo XS, Zhang X, Gold MJ, Khan S, Lee M, Huang C, Akbari M, Barrow F, Chan YT, Lei H, Kotoulas NK, Jovel J, Pastrello C, Kotlyar M, Goh C, Michelakis E, Clemente-Casares X, Ohashi PS, Engleman EG, Winer S, Jurisica I, Tsai S, Winer DA. Chakraborty M, et al. Among authors: lei h. Cell Rep. 2021 Jan 12;34(2):108609. doi: 10.1016/j.celrep.2020.108609. Cell Rep. 2021. PMID: 33440149 Free article.
3,919 results