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The CIF1 protein is a master orchestrator of trypanosome cytokinesis that recruits several cytokinesis regulators to the cytokinesis initiation site.
Zhou Q, An T, Pham KTM, Hu H, Li Z. Zhou Q, et al. Among authors: an t. J Biol Chem. 2018 Oct 19;293(42):16177-16192. doi: 10.1074/jbc.RA118.004888. Epub 2018 Aug 31. J Biol Chem. 2018. PMID: 30171070 Free PMC article.
Further analyses of the functional interplay between CIF1 and its associated proteins revealed a requirement of CIF1 for localization of a set of CIF1-associated proteins, an interdependence between KPP1 and CIF1, and an essential role of katanin in the completion o …
Further analyses of the functional interplay between CIF1 and its associated proteins revealed a requirement of CIF1 for localization of a s …
Faithful chromosome segregation in Trypanosoma brucei requires a cohort of divergent spindle-associated proteins with distinct functions.
Zhou Q, Lee KJ, Kurasawa Y, Hu H, An T, Li Z. Zhou Q, et al. Among authors: an t. Nucleic Acids Res. 2018 Sep 19;46(16):8216-8231. doi: 10.1093/nar/gky557. Nucleic Acids Res. 2018. PMID: 29931198 Free PMC article.
NuSAP2 is a highly divergent ASE1/PRC1/MAP65 homolog playing an essential role in promoting the G2/M transition. NuSAP3 is a kinetoplastid-specific Kif13-1-binding protein maintaining Kif13-1 protein stability and regulating the G2/M transition. Together, our work suggests …
NuSAP2 is a highly divergent ASE1/PRC1/MAP65 homolog playing an essential role in promoting the G2/M transition. NuSAP3 is a kinetopl …
Functional Analyses of Cytokinesis Regulators in Bloodstream Stage Trypanosoma brucei Parasites Identify Functions and Regulations Specific to the Life Cycle Stage.
Zhang X, An T, Pham KTM, Lun ZR, Li Z. Zhang X, et al. Among authors: an t. mSphere. 2019 May 1;4(3):e00199-19. doi: 10.1128/mSphere.00199-19. mSphere. 2019. PMID: 31043517 Free PMC article.
T. brucei undergoes an unusual mode of cytokinesis, which is controlled by a novel signaling cascade consisting of evolutionarily conserved protein kinases and trypanosome-specific regulatory proteins in the procyclic form. ...Together, these results identify conser …
T. brucei undergoes an unusual mode of cytokinesis, which is controlled by a novel signaling cascade consisting of evolutionar …
1,507 results