Spitz DR - Search Results

1

Emerging evidence for targeting mitochondrial metabolic dysfunction in cancer therapy.

Zhu Y, Dean AE, Horikoshi N, Heer C, Spitz DR, Gius D. Zhu Y, et al. Among authors: spitz dr. J Clin Invest. 2018 Aug 31;128(9):3682-3691. doi: 10.1172/JCI120844. Epub 2018 Aug 31. J Clin Invest. 2018. PMID: 30168803 Free PMC article. Review.

2

Redox factor-1 (Ref-1) mediates the activation of AP-1 in HeLa and NIH 3T3 cells in response to heat shock.

Diamond DA, Parsian A, Hunt CR, Lofgren S, Spitz DR, Goswami PC, Gius D. Diamond DA, et al. Among authors: spitz dr. J Biol Chem. 1999 Jun 11;274(24):16959-64. doi: 10.1074/jbc.274.24.16959. J Biol Chem. 1999. PMID: 10358044 Free article.

3

Cell cycle-coupled variation in topoisomerase IIalpha mRNA is regulated by the 3'-untranslated region. Possible role of redox-sensitive protein binding in mRNA accumulation.

Goswami PC, Sheren J, Albee LD, Parsian A, Sim JE, Ridnour LA, Higashikubo R, Gius D, Hunt CR, Spitz DR. Goswami PC, et al. Among authors: spitz dr. J Biol Chem. 2000 Dec 8;275(49):38384-92. doi: 10.1074/jbc.M005298200. J Biol Chem. 2000. PMID: 10986283 Free article.

4

Thioredoxin nuclear translocation and interaction with redox factor-1 activates the activator protein-1 transcription factor in response to ionizing radiation.

Wei SJ, Botero A, Hirota K, Bradbury CM, Markovina S, Laszlo A, Spitz DR, Goswami PC, Yodoi J, Gius D. Wei SJ, et al. Among authors: spitz dr. Cancer Res. 2000 Dec 1;60(23):6688-95. Cancer Res. 2000. PMID: 11118054

5

Increased activator protein 1 activity as well as resistance to heat-induced radiosensitization, hydrogen peroxide, and cisplatin are inhibited by indomethacin in oxidative stress-resistant cells.

Bradbury CM, Locke JE, Wei SJ, Rene LM, Karimpour S, Hunt C, Spitz DR, Gius D. Bradbury CM, et al. Among authors: spitz dr. Cancer Res. 2001 Apr 15;61(8):3486-92. Cancer Res. 2001. PMID: 11309312

6

Redox-sensitive interaction between KIAA0132 and Nrf2 mediates indomethacin-induced expression of gamma-glutamylcysteine synthetase.

Sekhar KR, Spitz DR, Harris S, Nguyen TT, Meredith MJ, Holt JT, Gius D, Marnett LJ, Summar ML, Freeman ML. Sekhar KR, et al. Among authors: spitz dr. Free Radic Biol Med. 2002 Apr 1;32(7):650-62. doi: 10.1016/s0891-5849(02)00755-4. Free Radic Biol Med. 2002. PMID: 11909699

7

Thioredoxin reductase regulates AP-1 activity as well as thioredoxin nuclear localization via active cysteines in response to ionizing radiation.

Karimpour S, Lou J, Lin LL, Rene LM, Lagunas L, Ma X, Karra S, Bradbury CM, Markovina S, Goswami PC, Spitz DR, Hirota K, Kalvakolanu DV, Yodoi J, Gius D. Karimpour S, et al. Among authors: spitz dr. Oncogene. 2002 Sep 12;21(41):6317-27. doi: 10.1038/sj.onc.1205749. Oncogene. 2002. PMID: 12214272

8

2-Deoxy-D-glucose-induced cytotoxicity and radiosensitization in tumor cells is mediated via disruptions in thiol metabolism.

Lin X, Zhang F, Bradbury CM, Kaushal A, Li L, Spitz DR, Aft RL, Gius D. Lin X, et al. Among authors: spitz dr. Cancer Res. 2003 Jun 15;63(12):3413-7. Cancer Res. 2003. PMID: 12810678

9

Thermal stress and the disruption of redox-sensitive signalling and transcription factor activation: possible role in radiosensitization.

Gius D, Mattson D, Bradbury CM, Smart DK, Spitz DR. Gius D, et al. Among authors: spitz dr. Int J Hyperthermia. 2004 Mar;20(2):213-23. doi: 10.1080/02656730310001619505. Int J Hyperthermia. 2004. PMID: 15195515 Free article. Review.

10

Heat shock and the activation of AP-1 and inhibition of NF-kappa B DNA-binding activity: possible role of intracellular redox status.

Mattson D, Bradbury CM, Bisht KS, Curry HA, Spitz DR, Gius D. Mattson D, et al. Among authors: spitz dr. Int J Hyperthermia. 2004 Mar;20(2):224-33. doi: 10.1080/02656730310001619956. Int J Hyperthermia. 2004. PMID: 15195516 Free article.

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