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Double genetic disruption of lactate dehydrogenases A and B is required to ablate the "Warburg effect" restricting tumor growth to oxidative metabolism.
Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M. Ždralević M, et al. Among authors: schnell a. J Biol Chem. 2018 Oct 12;293(41):15947-15961. doi: 10.1074/jbc.RA118.004180. Epub 2018 Aug 29. J Biol Chem. 2018. PMID: 30158244 Free PMC article.
Restricting Glycolysis Preserves T Cell Effector Functions and Augments Checkpoint Therapy.
Renner K, Bruss C, Schnell A, Koehl G, Becker HM, Fante M, Menevse AN, Kauer N, Blazquez R, Hacker L, Decking SM, Bohn T, Faerber S, Evert K, Aigle L, Amslinger S, Landa M, Krijgsman O, Rozeman EA, Brummer C, Siska PJ, Singer K, Pektor S, Miederer M, Peter K, Gottfried E, Herr W, Marchiq I, Pouyssegur J, Roush WR, Ong S, Warren S, Pukrop T, Beckhove P, Lang SA, Bopp T, Blank CU, Cleveland JL, Oefner PJ, Dettmer K, Selby M, Kreutz M. Renner K, et al. Among authors: schnell a. Cell Rep. 2019 Oct 1;29(1):135-150.e9. doi: 10.1016/j.celrep.2019.08.068. Cell Rep. 2019. PMID: 31577944 Free article.
Immunometabolic Markers in a Small Patient Cohort Undergoing Immunotherapy.
Hofbauer J, Hauck A, Matos C, Babl N, Decking SM, Rechenmacher M, Schulz C, Regotta S, Mickler M, Haferkamp S, Siska PJ, Herr W, Renner K, Kreutz M, Schnell A. Hofbauer J, et al. Among authors: schnell a. Biomolecules. 2022 May 18;12(5):716. doi: 10.3390/biom12050716. Biomolecules. 2022. PMID: 35625643 Free PMC article.
Vascular remodeling in systemic hypertension.
Gohlke P, Lamberty V, Kuwer I, Bartenbach S, Schnell A, Unger T. Gohlke P, et al. Among authors: schnell a. Am J Cardiol. 1993 Jun 24;71(17):2E-7E. doi: 10.1016/0002-9149(93)90945-9. Am J Cardiol. 1993. PMID: 8392281
188 results