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Alanine Scanning Mutagenesis of the MEDI4893 (Suvratoxumab) Epitope Reduces Alpha Toxin Lytic Activity In Vitro and Staphylococcus aureus Fitness in Infection Models.
Tkaczyk C, Semenova E, Shi YY, Rosenthal K, Oganesyan V, Warrener P, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: warrener p. Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01033-18. doi: 10.1128/AAC.01033-18. Print 2018 Nov. Antimicrob Agents Chemother. 2018. PMID: 30150481 Free PMC article.
Targeting Alpha Toxin and ClfA with a Multimechanistic Monoclonal-Antibody-Based Approach for Prophylaxis of Serious Staphylococcus aureus Disease.
Tkaczyk C, Hamilton MM, Sadowska A, Shi Y, Chang CS, Chowdhury P, Buonapane R, Xiao X, Warrener P, Mediavilla J, Kreiswirth B, Suzich J, Stover CK, Sellman BR. Tkaczyk C, et al. Among authors: warrener p. mBio. 2016 Jun 28;7(3):e00528-16. doi: 10.1128/mBio.00528-16. mBio. 2016. PMID: 27353753 Free PMC article.
Multimechanistic Monoclonal Antibodies (MAbs) Targeting Staphylococcus aureus Alpha-Toxin and Clumping Factor A: Activity and Efficacy Comparisons of a MAb Combination and an Engineered Bispecific Antibody Approach.
Tkaczyk C, Kasturirangan S, Minola A, Jones-Nelson O, Gunter V, Shi YY, Rosenthal K, Aleti V, Semenova E, Warrener P, Tabor D, Stover CK, Corti D, Rainey G, Sellman BR. Tkaczyk C, et al. Among authors: warrener p. Antimicrob Agents Chemother. 2017 Jul 25;61(8):e00629-17. doi: 10.1128/AAC.00629-17. Print 2017 Aug. Antimicrob Agents Chemother. 2017. PMID: 28584141 Free PMC article.
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa.
DiGiandomenico A, Keller AE, Gao C, Rainey GJ, Warrener P, Camara MM, Bonnell J, Fleming R, Bezabeh B, Dimasi N, Sellman BR, Hilliard J, Guenther CM, Datta V, Zhao W, Gao C, Yu XQ, Suzich JA, Stover CK. DiGiandomenico A, et al. Among authors: warrener p. Sci Transl Med. 2014 Nov 12;6(262):262ra155. doi: 10.1126/scitranslmed.3009655. Sci Transl Med. 2014. PMID: 25391481
Antibacterial Monoclonal Antibodies Do Not Disrupt the Intestinal Microbiome or Its Function.
Jones-Nelson O, Tovchigrechko A, Glover MS, Fernandes F, Rangaswamy U, Liu H, Tabor DE, Boyd J, Warrener P, Martinez J, Hilliard JJ, Stover CK, Yu W, DAngelo G, Hess S, Cohen TS, Sellman BR. Jones-Nelson O, et al. Among authors: warrener p. Antimicrob Agents Chemother. 2020 Apr 21;64(5):e02347-19. doi: 10.1128/AAC.02347-19. Print 2020 Apr 21. Antimicrob Agents Chemother. 2020. PMID: 32152087 Free PMC article.
44 results