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Early postnatal behavioral, cellular, and molecular changes in models of Huntington disease are reversible by HDAC inhibition.
Siebzehnrübl FA, Raber KA, Urbach YK, Schulze-Krebs A, Canneva F, Moceri S, Habermeyer J, Achoui D, Gupta B, Steindler DA, Stephan M, Nguyen HP, Bonin M, Riess O, Bauer A, Aigner L, Couillard-Despres S, Paucar MA, Svenningsson P, Osmand A, Andreew A, Zabel C, Weiss A, Kuhn R, Moussaoui S, Blockx I, Van der Linden A, Cheong RY, Roybon L, Petersén Å, von Hörsten S. Siebzehnrübl FA, et al. Among authors: riess o. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8765-E8774. doi: 10.1073/pnas.1807962115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150378 Free PMC article.
Transgenic rat model of Huntington's disease.
von Hörsten S, Schmitt I, Nguyen HP, Holzmann C, Schmidt T, Walther T, Bader M, Pabst R, Kobbe P, Krotova J, Stiller D, Kask A, Vaarmann A, Rathke-Hartlieb S, Schulz JB, Grasshoff U, Bauer I, Vieira-Saecker AM, Paul M, Jones L, Lindenberg KS, Landwehrmeyer B, Bauer A, Li XJ, Riess O. von Hörsten S, et al. Among authors: riess o. Hum Mol Genet. 2003 Mar 15;12(6):617-24. doi: 10.1093/hmg/ddg075. Hum Mol Genet. 2003. PMID: 12620967
Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats.
Kántor O, Temel Y, Holzmann C, Raber K, Nguyen HP, Cao C, Türkoglu HO, Rutten BP, Visser-Vandewalle V, Steinbusch HW, Blokland A, Korr H, Riess O, von Hörsten S, Schmitz C. Kántor O, et al. Among authors: riess o. Neurobiol Dis. 2006 Jun;22(3):538-47. doi: 10.1016/j.nbd.2005.12.014. Epub 2006 Feb 9. Neurobiol Dis. 2006. PMID: 16480885
Neurodegeneration and motor dysfunction in a conditional model of Parkinson's disease.
Nuber S, Petrasch-Parwez E, Winner B, Winkler J, von Hörsten S, Schmidt T, Boy J, Kuhn M, Nguyen HP, Teismann P, Schulz JB, Neumann M, Pichler BJ, Reischl G, Holzmann C, Schmitt I, Bornemann A, Kuhn W, Zimmermann F, Servadio A, Riess O. Nuber S, et al. Among authors: riess o. J Neurosci. 2008 Mar 5;28(10):2471-84. doi: 10.1523/JNEUROSCI.3040-07.2008. J Neurosci. 2008. PMID: 18322092 Free PMC article.
550 results