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Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice.
Wang Y, Su L, Morin MD, Jones BT, Mifune Y, Shi H, Wang KW, Zhan X, Liu A, Wang J, Li X, Tang M, Ludwig S, Hildebrand S, Zhou K, Siegwart DJ, Moresco EMY, Zhang H, Boger DL, Beutler B. Wang Y, et al. Among authors: beutler b. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):E8698-E8706. doi: 10.1073/pnas.1809232115. Epub 2018 Aug 27. Proc Natl Acad Sci U S A. 2018. PMID: 30150374 Free PMC article.
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection.
Tabeta K, Georgel P, Janssen E, Du X, Hoebe K, Crozat K, Mudd S, Shamel L, Sovath S, Goode J, Alexopoulou L, Flavell RA, Beutler B. Tabeta K, et al. Among authors: beutler b. Proc Natl Acad Sci U S A. 2004 Mar 9;101(10):3516-21. doi: 10.1073/pnas.0400525101. Epub 2004 Mar 1. Proc Natl Acad Sci U S A. 2004. PMID: 14993594 Free PMC article.
Akirins versus infection.
Beutler B, Moresco EM. Beutler B, et al. Nat Immunol. 2008 Jan;9(1):7-9. doi: 10.1038/ni0108-7. Nat Immunol. 2008. PMID: 18087247 No abstract available.
The serine protease TMPRSS6 is required to sense iron deficiency.
Du X, She E, Gelbart T, Truksa J, Lee P, Xia Y, Khovananth K, Mudd S, Mann N, Moresco EM, Beutler E, Beutler B. Du X, et al. Among authors: beutler e, beutler b. Science. 2008 May 23;320(5879):1088-92. doi: 10.1126/science.1157121. Epub 2008 May 1. Science. 2008. PMID: 18451267 Free PMC article.
A catechol-O-methyltransferase that is essential for auditory function in mice and humans.
Du X, Schwander M, Moresco EM, Viviani P, Haller C, Hildebrand MS, Pak K, Tarantino L, Roberts A, Richardson H, Koob G, Najmabadi H, Ryan AF, Smith RJ, Müller U, Beutler B. Du X, et al. Among authors: beutler b. Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14609-14. doi: 10.1073/pnas.0807219105. Epub 2008 Sep 15. Proc Natl Acad Sci U S A. 2008. PMID: 18794526 Free PMC article.
525 results