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Channelopathy as a SUDEP Biomarker in Dravet Syndrome Patient-Derived Cardiac Myocytes.
Frasier CR, Zhang H, Offord J, Dang LT, Auerbach DS, Shi H, Chen C, Goldman AM, Eckhardt LL, Bezzerides VJ, Parent JM, Isom LL. Frasier CR, et al. Among authors: offord j. Stem Cell Reports. 2018 Sep 11;11(3):626-634. doi: 10.1016/j.stemcr.2018.07.012. Epub 2018 Aug 23. Stem Cell Reports. 2018. PMID: 30146492 Free PMC article.
Altered cardiac electrophysiology and SUDEP in a model of Dravet syndrome.
Auerbach DS, Jones J, Clawson BC, Offord J, Lenk GM, Ogiwara I, Yamakawa K, Meisler MH, Parent JM, Isom LL. Auerbach DS, et al. Among authors: offord j. PLoS One. 2013 Oct 14;8(10):e77843. doi: 10.1371/journal.pone.0077843. eCollection 2013. PLoS One. 2013. PMID: 24155976 Free PMC article.
SCN1B-linked early infantile developmental and epileptic encephalopathy.
Aeby A, Sculier C, Bouza AA, Askar B, Lederer D, Schoonjans AS, Vander Ghinst M, Ceulemans B, Offord J, Lopez-Santiago LF, Isom LL. Aeby A, et al. Among authors: offord j. Ann Clin Transl Neurol. 2019 Dec;6(12):2354-2367. doi: 10.1002/acn3.50921. Epub 2019 Nov 11. Ann Clin Transl Neurol. 2019. PMID: 31709768 Free PMC article.
Sodium channel β1 subunits are post-translationally modified by tyrosine phosphorylation, S-palmitoylation, and regulated intramembrane proteolysis.
Bouza AA, Philippe JM, Edokobi N, Pinsky AM, Offord J, Calhoun JD, Lopez-Florán M, Lopez-Santiago LF, Jenkins PM, Isom LL. Bouza AA, et al. Among authors: offord j. J Biol Chem. 2020 Jul 24;295(30):10380-10393. doi: 10.1074/jbc.RA120.013978. Epub 2020 Jun 5. J Biol Chem. 2020. PMID: 32503841 Free PMC article.
Calcium channel alpha2-delta type 1 subunit is the major binding protein for pregabalin in neocortex, hippocampus, amygdala, and spinal cord: an ex vivo autoradiographic study in alpha2-delta type 1 genetically modified mice.
Bian F, Li Z, Offord J, Davis MD, McCormick J, Taylor CP, Walker LC. Bian F, et al. Among authors: offord j. Brain Res. 2006 Feb 23;1075(1):68-80. doi: 10.1016/j.brainres.2005.12.084. Epub 2006 Feb 3. Brain Res. 2006. PMID: 16460711
41 results