Antoniou MN - Search Results

1

An Optimized Lentiviral Vector Efficiently Corrects the Human Sickle Cell Disease Phenotype.

Weber L, Poletti V, Magrin E, Antoniani C, Martin S, Bayard C, Sadek H, Felix T, Meneghini V, Antoniou MN, El-Nemer W, Mavilio F, Cavazzana M, Andre-Schmutz I, Miccio A. Weber L, et al. Among authors: antoniou mn. Mol Ther Methods Clin Dev. 2018 Aug 4;10:268-280. doi: 10.1016/j.omtm.2018.07.012. eCollection 2018 Sep 21. Mol Ther Methods Clin Dev. 2018. PMID: 30140714 Free PMC article.

2

In vivo selection of genetically modified erythroblastic progenitors leads to long-term correction of beta-thalassemia.

Miccio A, Cesari R, Lotti F, Rossi C, Sanvito F, Ponzoni M, Routledge SJ, Chow CM, Antoniou MN, Ferrari G. Miccio A, et al. Among authors: antoniou mn. Proc Natl Acad Sci U S A. 2008 Jul 29;105(30):10547-52. doi: 10.1073/pnas.0711666105. Epub 2008 Jul 23. Proc Natl Acad Sci U S A. 2008. PMID: 18650378 Free PMC article.

3

Haemophilia B curative FIX production from a low dose UCOE-based lentiviral vector following hepatic pre-natal delivery.

Kao VY, Ferreira S, Waddington SN, Antoniou MN. Kao VY, et al. Among authors: antoniou mn. Curr Gene Ther. 2016 Nov 2. Online ahead of print. Curr Gene Ther. 2016. PMID: 27809754

4

The β-globin locus control region in combination with the EF1α short promoter allows enhanced lentiviral vector-mediated erythroid gene expression with conserved multilineage activity.

Montiel-Equihua CA, Zhang L, Knight S, Saadeh H, Scholz S, Carmo M, Alonso-Ferrero ME, Blundell MP, Monkeviciute A, Schulz R, Collins M, Takeuchi Y, Schmidt M, Fairbanks L, Antoniou M, Thrasher AJ, Gaspar HB. Montiel-Equihua CA, et al. Mol Ther. 2012 Jul;20(7):1400-9. doi: 10.1038/mt.2012.50. Epub 2012 Mar 20. Mol Ther. 2012. PMID: 22434141 Free PMC article.

5

Measurement of lentiviral vector titre and copy number by cross-species duplex quantitative PCR.

Christodoulou I, Patsali P, Stephanou C, Antoniou M, Kleanthous M, Lederer CW. Christodoulou I, et al. Gene Ther. 2016 Jan;23(1):113-8. doi: 10.1038/gt.2015.60. Epub 2015 Jun 30. Gene Ther. 2016. PMID: 26202078 Free PMC article.

6

Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes.

Fraser P, Pruzina S, Antoniou M, Grosveld F. Fraser P, et al. Genes Dev. 1993 Jan;7(1):106-13. doi: 10.1101/gad.7.1.106. Genes Dev. 1993. PMID: 8422981 Free article.

7

Transcriptional activation by hypersensitive site three of the human beta-globin locus control region in murine erythroleukemia cells.

Pruzina S, Antoniou M, Hurst J, Grosveld F, Philipsen S. Pruzina S, et al. Biochim Biophys Acta. 1994 Oct 18;1219(2):351-60. doi: 10.1016/0167-4781(94)90059-0. Biochim Biophys Acta. 1994. PMID: 7918632

8

Physiological levels of HBB transgene expression from S/MAR element-based replicating episomal vectors.

Sgourou A, Routledge S, Spathas D, Athanassiadou A, Antoniou MN. Sgourou A, et al. Among authors: antoniou mn. J Biotechnol. 2009 Aug 20;143(2):85-94. doi: 10.1016/j.jbiotec.2009.06.018. Epub 2009 Jun 25. J Biotechnol. 2009. PMID: 19559736

9

Thalassaemia mutations within the 5'UTR of the human beta-globin gene disrupt transcription.

Sgourou A, Routledge S, Antoniou M, Papachatzopoulou A, Psiouri L, Athanassiadou A. Sgourou A, et al. Br J Haematol. 2004 Mar;124(6):828-35. doi: 10.1111/j.1365-2141.2004.04835.x. Br J Haematol. 2004. PMID: 15009072 Free article.

10

Generation of a high-titer retroviral vector capable of expressing high levels of the human beta-globin gene.

Sadelain M, Wang CH, Antoniou M, Grosveld F, Mulligan RC. Sadelain M, et al. Proc Natl Acad Sci U S A. 1995 Jul 18;92(15):6728-32. doi: 10.1073/pnas.92.15.6728. Proc Natl Acad Sci U S A. 1995. PMID: 7624311 Free PMC article.

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