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Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.
Lahvic JL, Ammerman M, Li P, Blair MC, Stillman ER, Fast EM, Robertson AL, Christodoulou C, Perlin JR, Yang S, Chiang N, Norris PC, Daily ML, Redfield SE, Chan IT, Chatrizeh M, Chase ME, Weis O, Zhou Y, Serhan CN, Zon LI. Lahvic JL, et al. Among authors: robertson al. Proc Natl Acad Sci U S A. 2018 Sep 11;115(37):9252-9257. doi: 10.1073/pnas.1806077115. Epub 2018 Aug 23. Proc Natl Acad Sci U S A. 2018. PMID: 30139917 Free PMC article.
CHD7 and Runx1 interaction provides a braking mechanism for hematopoietic differentiation.
Hsu J, Huang HT, Lee CT, Choudhuri A, Wilson NK, Abraham BJ, Moignard V, Kucinski I, Yu S, Hyde RK, Tober J, Cai X, Li Y, Guo Y, Yang S, Superdock M, Trompouki E, Calero-Nieto FJ, Ghamari A, Jiang J, Gao P, Gao L, Nguyen V, Robertson AL, Durand EM, Kathrein KL, Aifantis I, Gerber SA, Tong W, Tan K, Cantor AB, Zhou Y, Liu PP, Young RA, Göttgens B, Speck NA, Zon LI. Hsu J, et al. Among authors: robertson al. Proc Natl Acad Sci U S A. 2020 Sep 22;117(38):23626-23635. doi: 10.1073/pnas.2003228117. Epub 2020 Sep 3. Proc Natl Acad Sci U S A. 2020. PMID: 32883883 Free PMC article.
Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.
Robertson AL, Ogryzko NV, Henry KM, Loynes CA, Foulkes MJ, Meloni MM, Wang X, Ford C, Jackson M, Ingham PW, Wilson HL, Farrow SN, Solari R, Flower RJ, Jones S, Whyte MK, Renshaw SA. Robertson AL, et al. Dis Model Mech. 2016 Jun 1;9(6):621-32. doi: 10.1242/dmm.024935. Epub 2016 Apr 14. Dis Model Mech. 2016. PMID: 27079522 Free PMC article.
A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.
Robertson AL, Holmes GR, Bojarczuk AN, Burgon J, Loynes CA, Chimen M, Sawtell AK, Hamza B, Willson J, Walmsley SR, Anderson SR, Coles MC, Farrow SN, Solari R, Jones S, Prince LR, Irimia D, Rainger GE, Kadirkamanathan V, Whyte MK, Renshaw SA. Robertson AL, et al. Sci Transl Med. 2014 Feb 26;6(225):225ra29. doi: 10.1126/scitranslmed.3007672. Sci Transl Med. 2014. PMID: 24574340 Free PMC article.
135 results