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RAP2 mediates mechanoresponses of the Hippo pathway.
Meng Z, Qiu Y, Lin KC, Kumar A, Placone JK, Fang C, Wang KC, Lu S, Pan M, Hong AW, Moroishi T, Luo M, Plouffe SW, Diao Y, Ye Z, Park HW, Wang X, Yu FX, Chien S, Wang CY, Ren B, Engler AJ, Guan KL. Meng Z, et al. Among authors: park hw. Nature. 2018 Aug;560(7720):655-660. doi: 10.1038/s41586-018-0444-0. Epub 2018 Aug 22. Nature. 2018. PMID: 30135582 Free PMC article.
Rag GTPases are cardioprotective by regulating lysosomal function.
Kim YC, Park HW, Sciarretta S, Mo JS, Jewell JL, Russell RC, Wu X, Sadoshima J, Guan KL. Kim YC, et al. Among authors: park hw. Nat Commun. 2014 Jul 1;5:4241. doi: 10.1038/ncomms5241. Nat Commun. 2014. PMID: 24980141 Free PMC article.
Metabolism. Differential regulation of mTORC1 by leucine and glutamine.
Jewell JL, Kim YC, Russell RC, Yu FX, Park HW, Plouffe SW, Tagliabracci VS, Guan KL. Jewell JL, et al. Among authors: park hw. Science. 2015 Jan 9;347(6218):194-8. doi: 10.1126/science.1259472. Epub 2015 Jan 7. Science. 2015. PMID: 25567907 Free PMC article.
A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.
Moroishi T, Park HW, Qin B, Chen Q, Meng Z, Plouffe SW, Taniguchi K, Yu FX, Karin M, Pan D, Guan KL. Moroishi T, et al. Among authors: park hw. Genes Dev. 2015 Jun 15;29(12):1271-84. doi: 10.1101/gad.262816.115. Genes Dev. 2015. PMID: 26109050 Free PMC article.
Alternative Wnt Signaling Activates YAP/TAZ.
Park HW, Kim YC, Yu B, Moroishi T, Mo JS, Plouffe SW, Meng Z, Lin KC, Yu FX, Alexander CM, Wang CY, Guan KL. Park HW, et al. Cell. 2015 Aug 13;162(4):780-94. doi: 10.1016/j.cell.2015.07.013. Cell. 2015. PMID: 26276632 Free PMC article.
1,579 results