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Novel, Self-Assembling Dimeric Inhibitors of Human β Tryptase.
Giardina SF, Werner DS, Pingle M, Feinberg PB, Foreman KW, Bergstrom DE, Arnold LD, Barany F. Giardina SF, et al. Among authors: bergstrom de. J Med Chem. 2020 Mar 26;63(6):3004-3027. doi: 10.1021/acs.jmedchem.9b01689. Epub 2020 Feb 27. J Med Chem. 2020. PMID: 32057241
Reversible linkage of two distinct small molecule inhibitors of Myc generates a dimeric inhibitor with improved potency that is active in myc over-expressing cancer cell lines.
Wanner J, Romashko D, Werner DS, May EW, Peng Y, Schulz R, Foreman KW, Russo S, Arnold LD, Pingle M, Bergstrom DE, Barany F, Thomson S. Wanner J, et al. Among authors: bergstrom de. PLoS One. 2015 Apr 15;10(4):e0121793. doi: 10.1371/journal.pone.0121793. eCollection 2015. PLoS One. 2015. PMID: 25875098 Free PMC article.
Target-Directed Self-Assembly of Homodimeric Drugs Against β-Tryptase.
Giardina SF, Werner DS, Pingle M, Foreman KW, Bergstrom DE, Arnold LD, Barany F. Giardina SF, et al. Among authors: bergstrom de. ACS Med Chem Lett. 2018 Jul 5;9(8):827-831. doi: 10.1021/acsmedchemlett.8b00204. eCollection 2018 Aug 9. ACS Med Chem Lett. 2018. PMID: 30128075 Free PMC article.
Synthesis and evaluation of new spacers for use as dsDNA end-caps.
Ng PS, Laing BM, Balasundarum G, Pingle M, Friedman A, Bergstrom DE. Ng PS, et al. Among authors: bergstrom de. Bioconjug Chem. 2010 Aug 18;21(8):1545-53. doi: 10.1021/bc100202y. Bioconjug Chem. 2010. PMID: 20715857 Free PMC article.
Endcaps for stabilizing short DNA duplexes.
Ng PS, Pingle MR, Balasundarum G, Friedman A, Zu X, Bergstrom DE. Ng PS, et al. Among authors: bergstrom de. Nucleosides Nucleotides Nucleic Acids. 2003 May-Aug;22(5-8):1635-7. doi: 10.1081/NCN-120023088. Nucleosides Nucleotides Nucleic Acids. 2003. PMID: 14565484
105 results