Roberts CM - Search Results

1

p53-Pirh2 Complex Promotes Twist1 Degradation and Inhibits EMT.

Yang-Hartwich Y, Tedja R, Roberts CM, Goodner-Bingham J, Cardenas C, Gurea M, Sumi NJ, Alvero AB, Glackin CA, Mor G. Yang-Hartwich Y, et al. Among authors: roberts cm. Mol Cancer Res. 2019 Jan;17(1):153-164. doi: 10.1158/1541-7786.MCR-18-0238. Epub 2018 Aug 21. Mol Cancer Res. 2019. PMID: 30131448 Free PMC article.

2

RNA-based TWIST1 inhibition via dendrimer complex to reduce breast cancer cell metastasis.

Finlay J, Roberts CM, Lowe G, Loeza J, Rossi JJ, Glackin CA. Finlay J, et al. Among authors: roberts cm. Biomed Res Int. 2015;2015:382745. doi: 10.1155/2015/382745. Epub 2015 Feb 11. Biomed Res Int. 2015. PMID: 25759817 Free PMC article.

3

Mesoporous silica nanoparticle delivery of chemically modified siRNA against TWIST1 leads to reduced tumor burden.

Finlay J, Roberts CM, Dong J, Zink JI, Tamanoi F, Glackin CA. Finlay J, et al. Among authors: roberts cm. Nanomedicine. 2015 Oct;11(7):1657-66. doi: 10.1016/j.nano.2015.05.011. Epub 2015 Jun 24. Nanomedicine. 2015. PMID: 26115637 Free PMC article.

4

TWIST1 drives cisplatin resistance and cell survival in an ovarian cancer model, via upregulation of GAS6, L1CAM, and Akt signalling.

Roberts CM, Tran MA, Pitruzzello MC, Wen W, Loeza J, Dellinger TH, Mor G, Glackin CA. Roberts CM, et al. Sci Rep. 2016 Nov 23;6:37652. doi: 10.1038/srep37652. Sci Rep. 2016. PMID: 27876874 Free PMC article.

5

Nanoparticle delivery of siRNA against TWIST to reduce drug resistance and tumor growth in ovarian cancer models.

Roberts CM, Shahin SA, Wen W, Finlay JB, Dong J, Wang R, Dellinger TH, Zink JI, Tamanoi F, Glackin CA. Roberts CM, et al. Nanomedicine. 2017 Apr;13(3):965-976. doi: 10.1016/j.nano.2016.11.010. Epub 2016 Nov 25. Nanomedicine. 2017. PMID: 27890656 Free PMC article.

6

Disruption of TWIST1-RELA binding by mutation and competitive inhibition to validate the TWIST1 WR domain as a therapeutic target.

Roberts CM, Shahin SA, Loeza J, Dellinger TH, Williams JC, Glackin CA. Roberts CM, et al. BMC Cancer. 2017 Mar 10;17(1):184. doi: 10.1186/s12885-017-3169-9. BMC Cancer. 2017. PMID: 28283022 Free PMC article.

7

Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer.

Wen W, Lowe G, Roberts CM, Finlay J, Han ES, Glackin CA, Dellinger TH. Wen W, et al. Among authors: roberts cm. Sci Rep. 2017 Oct 6;7(1):12754. doi: 10.1038/s41598-017-12922-2. Sci Rep. 2017. PMID: 28986550 Free PMC article.

8

Pterostilbene Suppresses Ovarian Cancer Growth via Induction of Apoptosis and Blockade of Cell Cycle Progression Involving Inhibition of the STAT3 Pathway.

Wen W, Lowe G, Roberts CM, Finlay J, Han ES, Glackin CA, Dellinger TH. Wen W, et al. Among authors: roberts cm. Int J Mol Sci. 2018 Jul 7;19(7):1983. doi: 10.3390/ijms19071983. Int J Mol Sci. 2018. PMID: 29986501 Free PMC article.

9

Protein kinase Cα-mediated phosphorylation of Twist1 at Ser-144 prevents Twist1 ubiquitination and stabilizes it.

Tedja R, Roberts CM, Alvero AB, Cardenas C, Yang-Hartwich Y, Spadinger S, Pitruzzello M, Yin G, Glackin CA, Mor G. Tedja R, et al. Among authors: roberts cm. J Biol Chem. 2019 Mar 29;294(13):5082-5093. doi: 10.1074/jbc.RA118.005921. Epub 2019 Feb 7. J Biol Chem. 2019. PMID: 30733340 Free PMC article.

10

The Role of Intra-Tumoral Heterogeneity and Its Clinical Relevance in Epithelial Ovarian Cancer Recurrence and Metastasis.

Roberts CM, Cardenas C, Tedja R. Roberts CM, et al. Cancers (Basel). 2019 Jul 30;11(8):1083. doi: 10.3390/cancers11081083. Cancers (Basel). 2019. PMID: 31366178 Free PMC article. Review.

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