Awadasseid A - Search Results

1

Design, synthesis and biological evaluation of novel TMPRSS2-PROTACs with florosubstituted 4-guanidino-N-phenylbenzamide derivative ligands.

Yang H, Xu H, Lin X, Cai Z, Xia Y, Wang Y, Chen Z, Zhang K, Wu Y, Wang J, Awadasseid A, Zhang W. Yang H, et al. Among authors: awadasseid a. Bioorg Med Chem. 2024 Dec 15;116:117982. doi: 10.1016/j.bmc.2024.117982. Epub 2024 Oct 31. Bioorg Med Chem. 2024. PMID: 39515209

2

Design, synthesis, anti-tumor activity and mechanism of novel PROTACs as degraders of PD-L1 and inhibitors of PD-1/PD-L1 interaction.

Zhang F, Yu Q, Wu C, Sun S, Wang Y, Wang R, Chen Z, Zhang H, Xiong X, Awadasseid A, Rao G, Zhao X, Zhang W. Zhang F, et al. Among authors: awadasseid a. Bioorg Med Chem. 2024 Sep 1;111:117867. doi: 10.1016/j.bmc.2024.117867. Epub 2024 Aug 3. Bioorg Med Chem. 2024. PMID: 39121678

3

Design, synthesis, and evaluation of antitumor activity of 2-arylmethoxy-4-(2-fluoromethyl-biphenyl-3-ylmethoxy) benzylamine derivatives as PD-1/PD-l1 inhibitors.

Zhang F, Zhang H, Zhou S, Plewka J, Wang M, Sun S, Wu C, Yu Q, Zhu M, Awadasseid A, Wu Y, Magiera-Mularz K, Zhang W. Zhang F, et al. Among authors: awadasseid a. Eur J Med Chem. 2024 Oct 5;276:116683. doi: 10.1016/j.ejmech.2024.116683. Epub 2024 Jul 15. Eur J Med Chem. 2024. PMID: 39032403

4

Recent advances and mechanisms of action of PD-L1 degraders as potential therapeutic agents.

Zhang F, Jiang R, Sun S, Wu C, Yu Q, Awadasseid A, Wang J, Zhang W. Zhang F, et al. Among authors: awadasseid a. Eur J Med Chem. 2024 Mar 15;268:116267. doi: 10.1016/j.ejmech.2024.116267. Epub 2024 Feb 23. Eur J Med Chem. 2024. PMID: 38422701 Review.

5

Small molecule and PROTAC molecule experiments in vitro and in vivo, focusing on mouse PD-L1 and human PD-L1 differences as targets.

Awadasseid A, Wang R, Sun S, Zhang F, Wu Y, Zhang W. Awadasseid A, et al. Biomed Pharmacother. 2024 Mar;172:116257. doi: 10.1016/j.biopha.2024.116257. Epub 2024 Feb 13. Biomed Pharmacother. 2024. PMID: 38350367 Free article. Review.

6

Repurposing and discovery of transmembrane serine protease 2 (TMPRSS2) inhibitors as prophylactic therapies for new coronavirus disease 2019 (COVID-19).

Yang H, Lin X, Yu Q, Awadasseid A, Zhang W. Yang H, et al. Among authors: awadasseid a. Pharmazie. 2023 Dec 4;78(11):217-224. doi: 10.1691/ph.2023.3578. Pharmazie. 2023. PMID: 38178286 Review.

7

A Review on the Anticancer Activity of Carbazole-based Tricyclic Compounds.

Zhang H, Zhang W, Zhu M, Awadasseid A. Zhang H, et al. Among authors: awadasseid a. Curr Med Chem. 2024;31(30):4826-4849. doi: 10.2174/0929867331666230825104254. Curr Med Chem. 2024. PMID: 37622700 Review.

8

Design, Synthesis, and Antitumor Activity Evaluation of 2-Arylmethoxy-4-(2,2'-dihalogen-substituted biphenyl-3-ylmethoxy) Benzylamine Derivatives as Potent PD-1/PD-L1 Inhibitors.

Zhang H, Zhou S, Plewka J, Wu C, Zhu M, Yu Q, Musielak B, Wang X, Awadasseid A, Magiera-Mularz K, Wu Y, Zhang W. Zhang H, et al. Among authors: awadasseid a. J Med Chem. 2023 Aug 10;66(15):10579-10603. doi: 10.1021/acs.jmedchem.3c00731. Epub 2023 Jul 26. J Med Chem. 2023. PMID: 37496104

9

PD-L1 dimerisation induced by biphenyl derivatives mediates anti-breast cancer activity via the non-immune PD-L1-AKT-mTOR/Bcl2 pathway.

Zhang H, Zhou SJ, Shen CF, Zhou YN, Wu CY, Zhu MY, Yu QM, Awadasseid A, Wu YL, Zhang W. Zhang H, et al. Among authors: awadasseid a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2230388. doi: 10.1080/14756366.2023.2230388. J Enzyme Inhib Med Chem. 2023. PMID: 37439326 Free PMC article.

10

Current studies and future promises of PD-1 signal inhibitors in cervical cancer therapy.

Awadasseid A, Zhou Y, Zhang K, Tian K, Wu Y, Zhang W. Awadasseid A, et al. Biomed Pharmacother. 2023 Jan;157:114057. doi: 10.1016/j.biopha.2022.114057. Epub 2022 Dec 1. Biomed Pharmacother. 2023. PMID: 36463828 Free article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

34 results

Search Page

Filters