Jones JP - Search Results

1

Kinetic mechanism of time-dependent inhibition of CYP2D6 by 3,4-methylenedioxymethamphetamine (MDMA): Functional heterogeneity of the enzyme and the reversibility of its inactivation.

Rodgers JT, Davydova NY, Paragas EM, Jones JP, Davydov DR. Rodgers JT, et al. Among authors: jones jp. Biochem Pharmacol. 2018 Oct;156:86-98. doi: 10.1016/j.bcp.2018.08.010. Epub 2018 Aug 13. Biochem Pharmacol. 2018. PMID: 30114388 Free PMC article.

2

The two faces of aldehyde oxidase: Oxidative and reductive transformations of 5-nitroquinoline.

Paragas EM, Humphreys SC, Min J, Joswig-Jones CA, Jones JP. Paragas EM, et al. Among authors: jones jp. Biochem Pharmacol. 2017 Dec 1;145:210-217. doi: 10.1016/j.bcp.2017.09.002. Epub 2017 Sep 6. Biochem Pharmacol. 2017. PMID: 28888950

3

Toward a systems approach to the human cytochrome P450 ensemble: interactions between CYP2D6 and CYP2E1 and their functional consequences.

Davydov DR, Davydova NY, Rodgers JT, Rushmore TH, Jones JP. Davydov DR, et al. Among authors: jones jp. Biochem J. 2017 Oct 10;474(20):3523-3542. doi: 10.1042/BCJ20170543. Biochem J. 2017. PMID: 28904078 Free PMC article.

4

Numerical Analysis of Time-Dependent Inhibition by MDMA.

Rodgers JT, Jones JP. Rodgers JT, et al. Among authors: jones jp. Drug Metab Dispos. 2020 Jan;48(1):1-7. doi: 10.1124/dmd.119.089268. Epub 2019 Oct 22. Drug Metab Dispos. 2020. PMID: 31641009 Free PMC article.

5

Enzyme Kinetics, Pharmacokinetics, and Inhibition of Aldehyde Oxidase.

Paragas EM, Choughule K, Jones JP, Barr JT. Paragas EM, et al. Among authors: jones jp. Methods Mol Biol. 2021;2342:257-284. doi: 10.1007/978-1-0716-1554-6_10. Methods Mol Biol. 2021. PMID: 34272698

6

Time Course of Aldehyde Oxidase and Why It Is Nonlinear.

Abbasi A, Paragas EM, Joswig-Jones CA, Rodgers JT, Jones JP. Abbasi A, et al. Among authors: jones jp. Drug Metab Dispos. 2019 May;47(5):473-483. doi: 10.1124/dmd.118.085787. Epub 2019 Feb 20. Drug Metab Dispos. 2019. PMID: 30787100 Free PMC article.

7

Aldehyde Oxidase Contributes to All-Trans-Retinoic Acid Biosynthesis in Human Liver.

Zhong G, Seaman CJ, Paragas EM, Xi H, Herpoldt KL, King NP, Jones JP, Isoherranen N. Zhong G, et al. Among authors: jones jp. Drug Metab Dispos. 2021 Mar;49(3):202-211. doi: 10.1124/dmd.120.000296. Epub 2020 Dec 18. Drug Metab Dispos. 2021. PMID: 33355213 Free PMC article.

8

ecoAO: A Simple System for the Study of Human Aldehyde Oxidases Role in Drug Metabolism.

Paragas EM, Humphreys SC, Min J, Joswig-Jones CA, Leimkühler S, Jones JP. Paragas EM, et al. Among authors: jones jp. ACS Omega. 2017 Aug 31;2(8):4820-4827. doi: 10.1021/acsomega.7b01054. Epub 2017 Aug 22. ACS Omega. 2017. PMID: 28884164 Free PMC article.

9

Identification of enzymes responsible for dantrolene metabolism in the human liver: A clue to uncover the cause of liver injury.

Amano T, Fukami T, Ogiso T, Hirose D, Jones JP, Taniguchi T, Nakajima M. Amano T, et al. Among authors: jones jp. Biochem Pharmacol. 2018 May;151:69-78. doi: 10.1016/j.bcp.2018.03.002. Epub 2018 Mar 6. Biochem Pharmacol. 2018. PMID: 29522712

10

Interspecies differences in the metabolism of methotrexate: An insight into the active site differences between human and rabbit aldehyde oxidase.

Choughule KV, Joswig-Jones CA, Jones JP. Choughule KV, et al. Among authors: jones jp. Biochem Pharmacol. 2015 Aug 1;96(3):288-95. doi: 10.1016/j.bcp.2015.05.010. Epub 2015 May 29. Biochem Pharmacol. 2015. PMID: 26032640 Free PMC article.

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