Matthies D - Search Results

1

Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs.

Matthies D, Bae C, Toombes GE, Fox T, Bartesaghi A, Subramaniam S, Swartz KJ. Matthies D, et al. Elife. 2018 Aug 15;7:e37558. doi: 10.7554/eLife.37558. Elife. 2018. PMID: 30109985 Free PMC article.

2

Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.

Prévost J, Chen Y, Zhou F, Tolbert WD, Gasser R, Medjahed H, Nayrac M, Nguyen DN, Gottumukkala S, Hessell AJ, Rao VB, Pozharski E, Huang RK, Matthies D, Finzi A, Pazgier M. Prévost J, et al. Among authors: matthies d. Nat Commun. 2023 Oct 23;14(1):6710. doi: 10.1038/s41467-023-42500-2. Nat Commun. 2023. PMID: 37872202 Free PMC article.

3

Structure of β-galactosidase at 3.2-Å resolution obtained by cryo-electron microscopy.

Bartesaghi A, Matthies D, Banerjee S, Merk A, Subramaniam S. Bartesaghi A, et al. Among authors: matthies d. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11709-14. doi: 10.1073/pnas.1402809111. Epub 2014 Jul 28. Proc Natl Acad Sci U S A. 2014. PMID: 25071206 Free PMC article.

4

2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor.

Bartesaghi A, Merk A, Banerjee S, Matthies D, Wu X, Milne JL, Subramaniam S. Bartesaghi A, et al. Among authors: matthies d. Science. 2015 Jun 5;348(6239):1147-51. doi: 10.1126/science.aab1576. Epub 2015 May 7. Science. 2015. PMID: 25953817 Free PMC article.

5

The crystal structure of human GlnRS provides basis for the development of neurological disorders.

Ognjenović J, Wu J, Matthies D, Baxa U, Subramaniam S, Ling J, Simonović M. Ognjenović J, et al. Among authors: matthies d. Nucleic Acids Res. 2016 Apr 20;44(7):3420-31. doi: 10.1093/nar/gkw082. Epub 2016 Feb 10. Nucleic Acids Res. 2016. PMID: 26869582 Free PMC article.

6

Cryo-EM Structures of the Magnesium Channel CorA Reveal Symmetry Break upon Gating.

Matthies D, Dalmas O, Borgnia MJ, Dominik PK, Merk A, Rao P, Reddy BG, Islam S, Bartesaghi A, Perozo E, Subramaniam S. Matthies D, et al. Cell. 2016 Feb 11;164(4):747-56. doi: 10.1016/j.cell.2015.12.055. Cell. 2016. PMID: 26871634 Free PMC article.

7

Using Cryo-EM to Map Small Ligands on Dynamic Metabolic Enzymes: Studies with Glutamate Dehydrogenase.

Borgnia MJ, Banerjee S, Merk A, Matthies D, Bartesaghi A, Rao P, Pierson J, Earl LA, Falconieri V, Subramaniam S, Milne JL. Borgnia MJ, et al. Among authors: matthies d. Mol Pharmacol. 2016 Jun;89(6):645-51. doi: 10.1124/mol.116.103382. Epub 2016 Apr 1. Mol Pharmacol. 2016. PMID: 27036132 Free PMC article.

8

Structural basis for early-onset neurological disorders caused by mutations in human selenocysteine synthase.

Puppala AK, French RL, Matthies D, Baxa U, Subramaniam S, Simonović M. Puppala AK, et al. Among authors: matthies d. Sci Rep. 2016 Aug 31;6:32563. doi: 10.1038/srep32563. Sci Rep. 2016. PMID: 27576344 Free PMC article.

9

Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.

Lai LTF, Balaraman J, Zhou F, Matthies D. Lai LTF, et al. Among authors: matthies d. Nat Commun. 2023 Nov 8;14(1):7207. doi: 10.1038/s41467-023-42599-3. Nat Commun. 2023. PMID: 37938562 Free PMC article.

10

The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins.

Miller AN, Houlihan PR, Matamala E, Cabezas-Bratesco D, Lee GY, Cristofori-Armstrong B, Dilan TL, Sanchez-Martinez S, Matthies D, Yan R, Yu Z, Ren D, Brauchi SE, Clapham DE. Miller AN, et al. Among authors: matthies d. Elife. 2023 Jan 25;12:e84477. doi: 10.7554/eLife.84477. Elife. 2023. PMID: 36695574 Free PMC article.

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