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Real-world data reveal a diagnostic gap in non-alcoholic fatty liver disease.
Alexander M, Loomis AK, Fairburn-Beech J, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Avillach P, Egger P, Kendrick S, Waterworth DM, Sattar N, Alazawi W. Alexander M, et al. BMC Med. 2018 Aug 13;16(1):130. doi: 10.1186/s12916-018-1103-x. BMC Med. 2018. PMID: 30099968 Free PMC article.
Risks and clinical predictors of cirrhosis and hepatocellular carcinoma diagnoses in adults with diagnosed NAFLD: real-world study of 18 million patients in four European cohorts.
Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Waterworth DM, Kendrick S, Sattar N, Alazawi W. Alexander M, et al. BMC Med. 2019 May 20;17(1):95. doi: 10.1186/s12916-019-1321-x. BMC Med. 2019. PMID: 31104631 Free PMC article.
Non-alcoholic fatty liver disease and risk of incident acute myocardial infarction and stroke: findings from matched cohort study of 18 million European adults.
Alexander M, Loomis AK, van der Lei J, Duarte-Salles T, Prieto-Alhambra D, Ansell D, Pasqua A, Lapi F, Rijnbeek P, Mosseveld M, Avillach P, Egger P, Dhalwani NN, Kendrick S, Celis-Morales C, Waterworth DM, Alazawi W, Sattar N. Alexander M, et al. BMJ. 2019 Oct 8;367:l5367. doi: 10.1136/bmj.l5367. BMJ. 2019. PMID: 31594780 Free PMC article.
Methotrexate and relative risk of dementia amongst patients with rheumatoid arthritis: a multi-national multi-database case-control study.
Newby D, Prieto-Alhambra D, Duarte-Salles T, Ansell D, Pedersen L, van der Lei J, Mosseveld M, Rijnbeek P, James G, Alexander M, Egger P, Podhorna J, Stewart R, Perera G, Avillach P, Grosdidier S, Lovestone S, Nevado-Holgado AJ. Newby D, et al. Among authors: alexander m. Alzheimers Res Ther. 2020 Apr 6;12(1):38. doi: 10.1186/s13195-020-00606-5. Alzheimers Res Ther. 2020. PMID: 32252806 Free PMC article.
Vascular and metabolic risk factor differences prior to dementia diagnosis: a multidatabase case-control study using European electronic health records.
Perera G, Rijnbeek PR, Alexander M, Ansell D, Avillach P, Duarte-Salles T, Gordon MF, Lapi F, Mayer MA, Pasqua A, Pedersen L, van Der Lei J, Visser PJ, Stewart R. Perera G, et al. Among authors: alexander m. BMJ Open. 2020 Nov 14;10(11):e038753. doi: 10.1136/bmjopen-2020-038753. BMJ Open. 2020. PMID: 33191253 Free PMC article.
Factors influencing longitudinal changes of circulating liver enzyme concentrations in subjects randomized to placebo in four clinical trials.
Nunez DJ, Alexander M, Yerges-Armstrong L, Singh G, Byttebier G, Fabbrini E, Waterworth D, Meininger G, Galwey N, Wallentin L, White HD, Vannieuwenhuyse B, Alazawi W, Kendrick S, Sattar N, Ferrannini E. Nunez DJ, et al. Among authors: alexander m. Am J Physiol Gastrointest Liver Physiol. 2019 Mar 1;316(3):G372-G386. doi: 10.1152/ajpgi.00051.2018. Epub 2018 Nov 29. Am J Physiol Gastrointest Liver Physiol. 2019. PMID: 30495974 Free article. Clinical Trial.
Treatment pathway analysis of newly diagnosed dementia patients in four electronic health record databases in Europe.
James G, Collin E, Lawrance M, Mueller A, Podhorna J, Zaremba-Pechmann L, Rijnbeek P, van der Lei J, Avillach P, Pedersen L, Ansell D, Pasqua A, Mosseveld M, Grosdidier S, Gungabissoon U, Egger P, Stewart R, Celis-Morales C, Alexander M, Novak G, Gordon MF. James G, et al. Among authors: alexander m. Soc Psychiatry Psychiatr Epidemiol. 2021 Mar;56(3):409-416. doi: 10.1007/s00127-020-01872-2. Epub 2020 Jun 3. Soc Psychiatry Psychiatr Epidemiol. 2021. PMID: 32494994
Dementia prevalence and incidence in a federation of European Electronic Health Record databases: The European Medical Informatics Framework resource.
Perera G, Pedersen L, Ansel D, Alexander M, Arrighi HM, Avillach P, Foskett N, Gini R, Gordon MF, Gungabissoon U, Mayer MA, Novak G, Rijnbeek P, Trifirò G, van der Lei J, Visser PJ, Stewart R. Perera G, et al. Among authors: alexander m. Alzheimers Dement. 2018 Feb;14(2):130-139. doi: 10.1016/j.jalz.2017.06.2270. Epub 2017 Jul 21. Alzheimers Dement. 2018. PMID: 28734783 Free article.
An exploratory phenome wide association study linking asthma and liver disease genetic variants to electronic health records from the Estonian Biobank.
James G, Reisberg S, Lepik K, Galwey N, Avillach P, Kolberg L, Mägi R, Esko T, Alexander M, Waterworth D, Loomis AK, Vilo J. James G, et al. Among authors: alexander m. PLoS One. 2019 Apr 12;14(4):e0215026. doi: 10.1371/journal.pone.0215026. eCollection 2019. PLoS One. 2019. PMID: 30978214 Free PMC article.
New genetic loci link adipose and insulin biology to body fat distribution.
Shungin D, Winkler TW, Croteau-Chonka DC, Ferreira T, Locke AE, Mägi R, Strawbridge RJ, Pers TH, Fischer K, Justice AE, Workalemahu T, Wu JMW, Buchkovich ML, Heard-Costa NL, Roman TS, Drong AW, Song C, Gustafsson S, Day FR, Esko T, Fall T, Kutalik Z, Luan J, Randall JC, Scherag A, Vedantam S, Wood AR, Chen J, Fehrmann R, Karjalainen J, Kahali B, Liu CT, Schmidt EM, Absher D, Amin N, Anderson D, Beekman M, Bragg-Gresham JL, Buyske S, Demirkan A, Ehret GB, Feitosa MF, Goel A, Jackson AU, Johnson T, Kleber ME, Kristiansson K, Mangino M, Leach IM, Medina-Gomez C, Palmer CD, Pasko D, Pechlivanis S, Peters MJ, Prokopenko I, Stančáková A, Sung YJ, Tanaka T, Teumer A, Van Vliet-Ostaptchouk JV, Yengo L, Zhang W, Albrecht E, Ärnlöv J, Arscott GM, Bandinelli S, Barrett A, Bellis C, Bennett AJ, Berne C, Blüher M, Böhringer S, Bonnet F, Böttcher Y, Bruinenberg M, Carba DB, Caspersen IH, Clarke R, Daw EW, Deelen J, Deelman E, Delgado G, Doney AS, Eklund N, Erdos MR, Estrada K, Eury E, Friedrich N, Garcia ME, Giedraitis V, Gigante B, Go AS, Golay A, Grallert H, Grammer TB, Gräßler J, Grewal J, Groves CJ, Haller T, Hallmans G, Hartman CA, Hassinen M, Hayward C, Heikkilä K, Herzig KH, Helmer Q, Hi… See abstract for full author list ➔ Shungin D, et al. Nature. 2015 Feb 12;518(7538):187-196. doi: 10.1038/nature14132. Nature. 2015. PMID: 25673412 Free PMC article.
3,579 results