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Distinguishing mode of action of compounds inducing craniofacial malformations in zebrafish embryos to support dose-response modeling in combined exposures.
Heusinkveld HJ, Schoonen WG, Hodemaekers HM, Nugraha A, Sirks JJ, Veenma V, Sujan C, Pennings JLA, Wackers PF, Palazzolo L, Eberini I, Rorije E, van der Ven LTM. Heusinkveld HJ, et al. Reprod Toxicol. 2020 Sep;96:114-127. doi: 10.1016/j.reprotox.2020.06.002. Epub 2020 Jun 15. Reprod Toxicol. 2020. PMID: 32553615 Free article.
The effects of aliphatic alcohols and related acid metabolites in zebrafish embryos - correlations with rat developmental toxicity and with effects in advanced life stages in fish.
van der Ven LTM, Schoonen WG, Groot RM, den Ouden F, Heusinkveld HJ, Zwart EP, Hodemaekers HM, Rorije E, de Knecht J. van der Ven LTM, et al. Among authors: heusinkveld hj. Toxicol Appl Pharmacol. 2020 Nov 15;407:115249. doi: 10.1016/j.taap.2020.115249. Epub 2020 Sep 24. Toxicol Appl Pharmacol. 2020. PMID: 32979392
A comprehensive view on mechanistic approaches for cancer risk assessment of non-genotoxic agrochemicals.
Luijten M, Corvi R, Mehta J, Corvaro M, Delrue N, Felter S, Haas B, Hewitt NJ, Hilton G, Holmes T, Jacobs MN, Jacobs A, Lamplmair F, Lewis D, Madia F, Manou I, Melching-Kollmuss S, Schorsch F, Schütte K, Sewell F, Strupp C, van der Laan JW, Wolf DC, Wolterink G, Woutersen R, Zvonar Z, Heusinkveld H, Braakhuis H. Luijten M, et al. Regul Toxicol Pharmacol. 2020 Dec;118:104789. doi: 10.1016/j.yrtph.2020.104789. Epub 2020 Oct 7. Regul Toxicol Pharmacol. 2020. PMID: 33035627 Free article. Review.
Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals.
Heusinkveld H, Braakhuis H, Gommans R, Botham P, Corvaro M, van der Laan JW, Lewis D, Madia F, Manou I, Schorsch F, Wolterink G, Woutersen R, Corvi R, Mehta J, Luijten M. Heusinkveld H, et al. Crit Rev Toxicol. 2020 Oct;50(9):725-739. doi: 10.1080/10408444.2020.1841732. Epub 2020 Nov 25. Crit Rev Toxicol. 2020. PMID: 33236972 Free article. Review.
Dose Addition in the Induction of Craniofacial Malformations in Zebrafish Embryos Exposed to a Complex Mixture of Food-Relevant Chemicals with Dissimilar Modes of Action.
Van Der Ven LTM, Van Ommeren P, Zwart EP, Gremmer ER, Hodemaekers HM, Heusinkveld HJ, van Klaveren JD, Rorije E. Van Der Ven LTM, et al. Among authors: heusinkveld hj. Environ Health Perspect. 2022 Apr;130(4):47003. doi: 10.1289/EHP9888. Epub 2022 Apr 8. Environ Health Perspect. 2022. PMID: 35394809 Free PMC article.
Letter to the editor regarding the review article by Yamada et al. (2021) titled "Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR)".
van Kesteren P, Pronk M, Heusinkveld H, Luijten M, Hakkert B. van Kesteren P, et al. Crit Rev Toxicol. 2022 May;52(5):397-398. doi: 10.1080/10408444.2022.2115875. Epub 2022 Sep 14. Crit Rev Toxicol. 2022. PMID: 36102316 Free article. Review. No abstract available.
38 results